Diagnosis and Treatment of Depression in Dialysis Patients

Kimura, Hiroyuki; Ozaki, Norio

doi:10.1111/j.1744-9987.2006.00385.x

Cited by 14 publications

(12 citation statements)

References 12 publications

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“…Although it was designed as a screening device rather than a diagnostic tool, health care providers sometimes use the DI‐MHD to reach a quick diagnosis. Our data show that the prevalence of depressive disorders among those who took the DI‐MHD was 21.9%, which is closer to the SCID‐I criteria than the BDI criteria and is similar to the results of other studies . Some reports indicate that the prevalence of depressive disorders is very high ; however, in addition to the use of different detection scales, cutoff values, populations, and regions, nonspecific detection scales are an important reason for discrepant results and were the motivation for creating the DI‐MHD.…”

Section: Discussionsupporting

confidence: 86%

Development and Preliminary Validation of a Depression Assessment Tool for Maintenance Hemodialysis Patients

et al. 2018

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Patients undergoing maintenance hemodialysis (MHD) are subject to a higher-than-usual prevalence of depressive disorders. However, the lack of consensus regarding the best assessment method remains an important problem. Thus, there is a clear need for more effective screening tools and an easily administered, disease-specific self-report measure of depression in MHD patients. After we developed and administered an initial depression inventory for MHD patients (I-DI-MHD), we created the DI-MHD and administered the DI-MHD and the Beck Depression Inventory (BDI) to 354 patients from four hospitals. Reliability, construct validity and receiver operator characteristic curves were assessed. The 17-item DI-MHD instrument displayed good internal consistency (Cronbach's alpha =0.893), provided excellent convergent validity, and correlated with the BDI scale (kappa =0.785, P <0.001). A factor analysis pattern matrix analysis showed that a four-factor model provided the best account of the data. Finally, the DI-MHD cutoff yielded a sensitivity of 0.97 and a specificity of 0.86, which were slightly better than the corresponding values for the BDI. The DI-MHD scale shows reasonable validity and reliability for assessing depression in MHD patients.

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Section: Discussionsupporting

confidence: 86%

Development and Preliminary Validation of a Depression Assessment Tool for Maintenance Hemodialysis Patients

et al. 2018

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“…Studies have demonstrated the effectiveness of treatments for several of the conditions, including impaired physical function (6,30), pain (31), and depression (32,33). The co-occurrence of multiple conditions would appear to be a formidable barrier to their successful treatment because of the need for many interventions.…”

Section: Discussionmentioning

confidence: 99%

Relationship between Conditions Addressed by Hemodialysis Guidelines and Non-ESRD-Specific Conditions Affecting Quality of Life

Leinau

Murphy

Bradley

et al. 2009

Clinical Journal of the American Society of Nephrology

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Background and objectives: Persons with ESRD identify non-disease-specific conditions as negatively affecting their quality of life. It is unknown how these non-ESRD-specific conditions correlate with each other and with ESRD-specific conditions such as anemia, renal osteodystrophy, dialysis access, and dialysis adequacy. The objectives of this study were to determine the prevalence and inter-relatedness of selected conditions among persons receiving hemodialysis and to analyze the relationship between non-ESRD-specific and ESRD-specific conditions. Design, setting, participants, & measurements: This was an observational cohort study of persons with ESRD that included standardized assessments for pain, fatigue, depression, cognitive impairment, and impaired physical performance. The study was conducted at three dialysis clinics in one urban geographic area. Of the 134 persons who met exclusion criteria, 25 declined participation, yielding a sample size of 109.Results: Pain was present in >81% of participants, fatigue and impaired physical performance in >60% participants, and cognitive impairment and depression in >25% of participants. Pain, fatigue, and depression were highly correlated, but had no correlation with use of a catheter for access, hemoglobin (Hgb), intact parathyroid hormone (iPTH), phosphorous, or Kt/V values outside of the range of guidelines. There was a modest correlation between cognitive function and both Hgb and iPTH.Conclusions: Non-ESRD-specific conditions such as fatigue, pain, and depression are as prevalent as ESRD-specific conditions, and the magnitude of the correlations between the non-ESRD-specific conditions is greater than the correlations between non-ESRD-specific and ESRD-specific conditions. Current guidelines may be failing to address a substantial component of the disease burden for persons with ESRD.

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“…Educating staff and patients may promote earlier detection and treatment [109]. Employing a more holistic approach may be the most effective form of treatment for dialysis patients [110]. …”

Section: Treatmentmentioning

confidence: 99%

Depression on Dialysis

et al. 2008

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Depression is the most common psychopathological condition among patients with end-stage renal disease (ESRD), yet it is still under-recognized and misdiagnosed. Depression reduces quality of life and has a negative clinical impact upon sufferers with chronic illness, including ESRD. This article discusses the negative effects of depression among the ESRD population treated with dialysis, the prevalence of the condition, the methodological issues involved with screening and treatment, and the possible psychological and somatic causes. There is a need to identify the prevalence of the disorder by effective methods, overcome the current issues surrounding depression assessment and to undertake trials of suitable treatments.

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Diagnosis and Treatment of Depression in Dialysis Patients

Cited by 14 publications

References 12 publications

Development and Preliminary Validation of a Depression Assessment Tool for Maintenance Hemodialysis Patients

Development and Preliminary Validation of a Depression Assessment Tool for Maintenance Hemodialysis Patients

Relationship between Conditions Addressed by Hemodialysis Guidelines and Non-ESRD-Specific Conditions Affecting Quality of Life

Depression on Dialysis

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