Diagnosis and treatment of bronchopulmonary neuroendocrine tumours: State of the art

Tabaksblat, Elizaveta Mitkina; Langer, Seppo W.; Knigge, Ulrich; Grønbæk, Henning; Mortensen, Jann; Petersen, René Horsleben; Federspiel, Birgitte; Ladekarl, Morten

doi:10.3109/0284186x.2015.1067715

Cited by 16 publications

(15 citation statements)

References 113 publications

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“…For BP NEN, typical and atypical carcinoids as well as large-cell neuroendocrine carcinomas have been included as per ENETS guidelines [7] and Danish guidelines [8] . Smallcell lung cancer is not included in the article as it is beyond the scope of these recommendations and as it is dealt with in several other guidelines.…”

Section: Documentation At Follow-up Should Adhere To the Present Who mentioning

confidence: 99%

ENETS Consensus Recommendations for the Standards of Care in Neuroendocrine Neoplasms: Follow-Up and Documentation

Knigge

Capdevila²,

Bartsch³

et al. 2017

Neuroendocrinology

108

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ENETS consensus recommendations for the standards of care in neuroendocrine neoplasms (NEN) concerning follow-up and documentation are considered in this review. The documentation of patients with NEN should include the most relevant data characterizing an individual patient from the first contact with his/her physician/hospital until his/her last presentation during follow-up. It is advocated that follow-up occurs in specialized NEN centers with regular NEN tumor boards with expert panels. The follow-up should be in accordance with the ENETS consensus guidelines from 2011 and 2016, the present and coming WHO classification and ENETS/UICC recommendations for TNM staging. The recommendations for follow-up in patients with thymic, bronchopulmonary and gastroenteropancreatic NEN are given in Table 1. However, it should be stressed that evidence-based studies for follow-up are largely missing.

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Section: Documentation At Follow-up Should Adhere To the Present Who mentioning

confidence: 99%

ENETS Consensus Recommendations for the Standards of Care in Neuroendocrine Neoplasms: Follow-Up and Documentation

Knigge

Capdevila²,

Bartsch³

et al. 2017

Neuroendocrinology

108

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“…Pueden tener calcificaciones excéntricas o difusas que recuerdan a la broncolitiasis y rara vez se cavitan [6][7][8][9] . Debido a su naturaleza vascular captan el contraste de forma ávida y homogénea 10 . Se pueden asociar a adenopatías hiliares o mediastinales bien sea por procesos infecciosos o metastásicos 7 .…”

Section: Discussionunclassified

“…Sin embargo, si la obstrucción es completa, se producen atelectasias y neumonías recurrentes que con el tiempo pueden llevar a bronquiectasias y abscesos 3 . Cuando son periféricos se comportan como lesiones redondeadas u ovaladas de contornos lisos o lobulados y aunque tienen un lento crecimiento en su mayoría son carcinoides atípicos de grado intermedio con mayor probabilidad de metastatizar [7][8][9][10] .…”

Section: Discussionunclassified

“…La TC con contraste endovenoso es la "prueba de oro" para el estudio radiológico de los tumores carcinoides, ya que este permite identificar los diferentes componentes de la lesión, bien sea intraluminares, murales y extrabronquiales, además de la presencia de adenopatías y el realce tumoral para una adecuada estadificación [8][9][10] . No obstante, la broncoscopía convencional tiene participación en el diagnóstico, su utilidad radica en la resolución de los síntomas obstructivos así como alternativa terapéutica a la cirugía 9,10 .…”

Section: Discussionunclassified

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Hallazgos por imagen de tumor carcinoide bronquial en hospital de La Habana

2019

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Se presenta un caso de adolescente sin comorbilidades, quien cursó durante tres meses con infecciones respiratorias a repetición sin mejoría a pesar de manejo médico apropiado. En imagen de control posterior a la hospitalización, se documenta en estudios de imagen lesión del lóbulo inferior derecho con crecimiento endoluminal y mediante broncoscopía se confirma la presencia de una masa tumoral en la luz del bronquio para dicho lóbulo. Se realiza biopsia y el estudio anatomopatológico reporta tumor carcinoide variedad típica. A pesar que es una entidad poco frecuente, el tumor carcinoide es una neoplasia neuroendócrina que se puede presentar en el sistema respiratorio en este grupo poblacional y se debe considerar en el contexto de infecciones respiratorias a repetición. Los estudios de imagen deberían ser parte de la evaluación de todo paciente que cursa con complicaciones de infecciones respiratorias y en el diagnóstico diferencial de otras entidades respiratorias.

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“…CA have a high incidence of recurrence, especially in N+. 2,27 The histological subtype and the condition of the lymph nodes are the most important prognostic factors. 1,28,29 Data on follow-up are controversial, long follow-up periods of up to 20 years 1 are generally recommended.…”

Section: Introductionmentioning

confidence: 99%

Experiencia institucional en México en el manejo quirúrgico de tumores carcinoides pulmonares

Iñiguez-García¹,

Valencia-Sánchez²,

Armas-Zárate³

2021

NCT Neumología Y Cirugía De Tórax

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Lung carcinoid tumors are a rare pathology, representing only 1-5% of all pulmonary neoplasms, with estimated incidence of 5-10/1,000,000 people/year. The purpose of this study is to describe the incidence, clinical and pathological characteristics, and their outcomes, in patients diagnosed with carcinoid tumor in a single institution. Material and methods: Retrospective analysis of patients diagnosed with carcinoid tumor undergoing surgical resection at the National Institute of Respiratory Diseases (INER) from March 2013-to December 2019. Demographic, pathological, clinical, treatment and follow-up data were collected and analyzed. Results: 30 patients diagnosed with carcinoid tumor were found. The median age was 47.2 years. The most common symptoms of presentation were progressive dyspnea and hemoptysis. The tumor appeared predominantly on the right side and lower lobes. Diagnosis was made preoperatively through bronchoscopy in most cases. Conclusions: Pulmonary carcinoid tumors (PCT) are relatively rare pulmonary neoplasms that occur with nonspecific and long-evolving symptoms. Surgical resection is required for treatment, and where feasible, with the greatest preservation of lung tissue possible. This leads to excellent local control and high long-term survival.

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Diagnosis and treatment of bronchopulmonary neuroendocrine tumours: State of the art

Cited by 16 publications

References 113 publications

ENETS Consensus Recommendations for the Standards of Care in Neuroendocrine Neoplasms: Follow-Up and Documentation

ENETS Consensus Recommendations for the Standards of Care in Neuroendocrine Neoplasms: Follow-Up and Documentation

Hallazgos por imagen de tumor carcinoide bronquial en hospital de La Habana

Experiencia institucional en México en el manejo quirúrgico de tumores carcinoides pulmonares

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