Diagnosis and treatment considerations of atypical oral pain in tuberous sclerosis

Goyal, Lata; Agarwal, Padmanidhi; Reddy, Gosla Srinivas; Jain, Kanika

doi:10.4103/jfmpc.jfmpc_1213_19

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…18 There are dramatic similarities between neuropathic orofacial pain and tooth pain with other maxillofacial pathologic pains in the cervico-facial region that leads to incorrect diagnoses followed by invasive and irreversible inappropriate treatments. 19 Because of odontogenic pain like manifestations of TN, sufferers generally consult dental professionals first and may be treated for a unconfirmed suspicious dental cause before being adequately diagnosed or referred to a maxillofacial surgeon and neurologist/ neurosurgeon. 20 Unfortunately, a certain percentage of them receive unnecessary dental treatment because of the mixed characteristics of the symptoms which frequently resemble dental conditions.…”

Section: Clinical Relevancementioning

confidence: 99%

Trigeminal neuralgia and associated unwarranted dental treatment

Agarwal

Bhatt²,

Jain³

et al. 2021

Oral Surgery

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Pain is a universal phenomenon of complex human psychophysiological experience which has evolved from a onedimensional sensation to a multi-dimensional one. 1 The most challenging and rewarding aspects of dental practice is the identification and management of the patient's pain. 2 Unfortunately, most diagnostic procedures are often restricted to identifying a suspected tooth rather than considering possible non-odontogenic sources of pain. 3 Persistent and chronic pain are more prevalent in the cervico-facial region than others. Oro-facial pain encompasses an amalgamation of manifestations within and outside the oral cavity. 4 Pain of neural origin is produced by changes in neurological function or structure, unlike the pain receptors excitation that occurs in nociceptive pain. 5 They occur along a nerve distribution that occasionally confers tooth pain, which frequently becomes a diagnostic difficulty for the general dental practitioner.Trigeminal neuralgia (TN) is a neuropathy of the trigeminal nerve having episodes of unilateral extreme, stabbing, electric shock-like twinge in the facial region innervated by

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Section: Clinical Relevancementioning

confidence: 99%

Trigeminal neuralgia and associated unwarranted dental treatment

Agarwal

Bhatt²,

Jain³

et al. 2021

Oral Surgery

Self Cite

View full text Add to dashboard Cite

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Oral manifestations of tuberous sclerosis complex: A systematic review

Panwar,

Malik,

Kamarthi

et al. 2024

Pediatric Dental Journal

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Diagnostic features of tuberous sclerosis complex: case report and literature review

Alshoabi¹,

Hamid²,

Alhazmi³

et al. 2022

Quant Imaging Med Surg

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Tuberous sclerosis complex (TSC) is a rare autosomal dominant genetic syndrome that is caused by mutations in the tumour suppressor genes TSC1 or TSC2 which causes multiorgan growths. TSC presents at any age as a wide range of clinical and phenotypic manifestations with varying severity. The main goal of this article was to state two cases of TSC and review the most commonly reported major and minor diagnostic clinical features and the most common features that led to an investigation of possible TSC diagnosis. Herein, we report two cases of TSC, which both presented with seizures during the first 6 months of life. Case 1 presented with multiple types of seizures from 6 months of age and was diagnosed by multiple calcified subependymal nodules (SENs) detected by computed tomography and magnetic resonance imaging (MRI). Case 2 presented with seizures from 3 months of age and was diagnosed prenatally when a tumour was seen in her heart during antenatal ultrasonography. In conclusion, the literature review revealed that neurological manifestations (mainly seizures) were the main feature that led to investigation and diagnosis of TSC followed by abdominal manifestations (mainly renal features) and antenatal follow-up imaging.Other manifestations in skin, chest, eyes, teeth and heart rarely led to TSC diagnosis. In some cases, TSC was incidentally discovered by medical imaging. The cortical tubers, SENs, and subependymal giant cell astrocytomas brain lesions were the most commonly reported major features. Skin features including angiofibromas, ungual fibromas and shagreen patch were the second most common major features reported in the literature. However, skin manifestations were not a common led to investigation and diagnosis of TSC. Renal features, mainly angiomyolipomas (AMLs), were the third most common major feature reported. Medical imaging plays an essential role in diagnosis of TSC, and clinical features are important clues that lead to investigation for the disease.

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Diagnosis and treatment considerations of atypical oral pain in tuberous sclerosis

Cited by 3 publications

References 10 publications

Trigeminal neuralgia and associated unwarranted dental treatment

Trigeminal neuralgia and associated unwarranted dental treatment

Oral manifestations of tuberous sclerosis complex: A systematic review

Diagnostic features of tuberous sclerosis complex: case report and literature review

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