“…Uterine serous carcinoma (USC) is an aggressive subtype of endometrial cancer, accounting for a disproportionate number of uterine cancer-related deaths. Najjar et al provide a comprehensive and detailed overview of the diagnostic approaches and management of USC, including pre-operative diagnostic and prognostic tools, surgical staging and pathology, pathogenesis and tumor markers, adjuvant, early, late and recurrent stage disease management [4]. They describe the significant advances that have been made in characterizing the molecular landscape and the potential for a number of different targeted therapies.…”