Diagnosis and Management of Primary Umbilical Melanoma with Omphalitis Features

Song, Yinjing; Xu, Dong; Sun, Lin; Ding, Kun; Hu, Yan; Yuan, Yunfei

doi:10.1159/000350421

Cited by 5 publications

(4 citation statements)

References 23 publications

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“…Primary cutaneous malignant melanoma involving the umbilicus is a rare entity and, to our knowledge, only 32 cases have been described in the literature since 1975 (9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24). Given the anatomical site of the umbilicus, lymphatic drainage and thus dissemination, may occur to the inguinal area and to the axilla (25), but also to parailiac lymph nodes, even without involvement of the superficial inguinal nodes.…”

Section: Discussionmentioning

confidence: 99%

SPECT/CT-Guided Surgical Removal of a Positive External Iliac Sentinel Node in Primary Umbilical Melanoma: Report of a Case, and Up-to-Date Review of the Literature

et al. 2022

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Primary umbilical melanoma is rare tumor, representing about 5% of all umbilical malignancies.The lymphatic drainage from the tumor is challenging and can be to inguinal, axillary and retroperitoneal nodes. Dynamic and static lymphoscintigraphy with single-photon emission tomography/computed tomography (SPECT/CT) and sentinel lymph node biopsy (SLNB) is a widely validated technique in patients with clinically localized melanoma to search for and quantify nodal spread of cutaneous melanoma. Moreover, it offers the surgeon the preoperative information about the number and location of the sentinel lymph nodes (SLNs), which makes SLNB easier and quicker. This is the first report of an ulcerated thick melanoma of the umbilicus metastasizing only to an external iliac lymph-node without involvement of superficial inguinal SLNs. The preoperative high-resolution ultrasound (HR-US) examination of the regional lymph node field had been normal. This case-report shows how addition of SPECT/CT to planar imaging in a patient with clinically localized umbilical melanoma can help avoid incomplete SLNB when a deep SLN is not removed. A literature review of umbilical melanoma is also provided.

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Section: Discussionmentioning

confidence: 99%

SPECT/CT-Guided Surgical Removal of a Positive External Iliac Sentinel Node in Primary Umbilical Melanoma: Report of a Case, and Up-to-Date Review of the Literature

et al. 2022

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“…It is well known that the melanoma of the skin is one of the most malignant tumors and that can occur in any region of the body. Melanoma arising in the umbilicus, as a primary tumor, is very rare, with unknown worldwide incidence statistics [9][10][11][12][13][14] . The first description of primary umbilical melanoma was made by Cullen in 1916, who described three patients 9 .…”

Section: Discussionmentioning

confidence: 99%

“…The first description of primary umbilical melanoma was made by Cullen in 1916, who described three patients 9 . There are a few other reports of the primary melanoma of the umbilicus [10][11][12][13][14] . Those reports are about melanoma in the typical form and of smaller size.…”

Section: Discussionmentioning

confidence: 99%

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Atypical primary melanoma of the umbilicus: A case report

Vulović

Kozarski

Petrović

et al. 2018

VSP

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Introduction. The umbilicus (omphalos; the navel; belly button; tummy button) is important in a medical and psychosocial context. Umbilical tumors are rare and can be benign or malignant, primary or secondary. The most common are malignant metastatic tumors, especially The Sister Mary Joseph Nodule, an eponym for the umbilical metastasis of intra-abdominal malignant tumors. Primary melanoma of the umbilicus is very rare, there is few literature data about it and its incidence is not well known. Therefore, the aim of this study was to present a patient with a rare localization of the primary skin melanoma, that was, also, of atypical form, large and involved the whole umbilicus and surrounding skin. Case Report. In this report, the patient had nodular red tumor which involved the whole umbilicus. Tumor had rapid growth. In the differential diagnosis, the tumor most by resembled a pyogenic granuloma. After the surgery, the histopathological finding showed the primary nodular skin melanoma (Clark V, Breslow 10 mm, positive for: vimentim S-100 protein, melan-A and HMB-45, and negative for EMA, with moderately high proliferative activity). Conclussion. According to literature data, this is 27th case of the primary melanoma of the umbilicus since 1916 when it was first reported. By presenting this rare clinical case, we emphasize that any skin lesion that is removed, must be sent to a histopathologic analysis.

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Umbilical Neoplasm

Fahmy¹

2018

Umbilicus and Umbilical Cord

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Diagnosis and Management of Primary Umbilical Melanoma with Omphalitis Features

Cited by 5 publications

References 23 publications

SPECT/CT-Guided Surgical Removal of a Positive External Iliac Sentinel Node in Primary Umbilical Melanoma: Report of a Case, and Up-to-Date Review of the Literature

SPECT/CT-Guided Surgical Removal of a Positive External Iliac Sentinel Node in Primary Umbilical Melanoma: Report of a Case, and Up-to-Date Review of the Literature

Atypical primary melanoma of the umbilicus: A case report

Umbilical Neoplasm

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