Diagnosis and Management of Odontogenic Myxoma in a Dog

Abstract

A three-year-old Jack Russell terrier dog was presented with a large gingival mass of the right mandible extending from the fourth premolar to the first molar teeth. Radiographic examination of the expansile mass revealed moth-eaten, honeycomb-like lyses of the mandible and extended into the mandibular alveolar canal based on computed tomography. The histopathological diagnosis of the biopsy was odontogenic fibromyxoma. Mandibulectomy with resection of the associated soft tissues was performed. Surgical management was curative with no clinical signs of disease 2-years after treatment. These neoplasms are slow growing, locally destructive tumors of odontogenic origin that have been described in the jaw of only one dog. In this paper, the clinico-radiological and pathologic features, diagnostic modalities as well as the factors that might influence treatment outcome of odontogenic myxomas are discussed. These odontogenic tumors are currently excluded from the WHO classification of odontogenic tumors in domestic animals and inclusion in future classifications systems is proposed.

Bokser Irkı 12 Yaşlı Bir Köpekte Rastlanan Kutanöz Miksoma Olgusu

“…This agressive behaviour was consistent with the tumor's locally invasive growth reported in literature 14 .…”

“…These masses are seen at extremities, back and groin 14 . Clinically cutaneous myxomas may be hard, elastic or soft in consistency.…”

Odontogenic Myxoma in an 8-Year-Old Labrador Retriever Dog

“…7,8,12 Of the few cases documented in domestic animals, 1 report was in a 1.5-year-old mixed breed filly, 1 another in a 12-year-old female Doberman Pincher, 5 and the most recent cases were in a 14-year-old male Dachshund 2 and a 3-year-old Jack Russell terrier. 10 The current report compares the gross, microscopic, and prognostic attributes seen in the present tumor with those described in the other 3 canine OM cases reported elsewhere (Table 1). 2,5,10 A formalin-fixed biopsy from an 8-year-old Labrador Retriever was received for histologic evaluation at the North Dakota State University, Veterinary Diagnostic Laboratory (Fargo, North Dakota).…”

“…Accurate diagnosis of these tumors, therefore, is of paramount importance because these tumors frequently show aggressive behavior, despite a deceptively slow growth pattern. 5,10 Odontogenic myxoma (OM) is a benign but locally invasive OT variant of mesenchymal origin that arises from the dental papilla, dental follicle, and periodontal ligament. 13,15 Also called odontogenic fibromyxoma, OM has been reported at a very low frequency in human beings 4,8,9,11 and is extremely rare in domestic animals.…”

Detection of arenavirus in a peripheral odontogenic fibromyxoma in a red tail boa (Boa constrictor constrictor) with inclusion body disease

“…7 The predominant slow growth and a 2-year interval before recurrence of the neoplasia as noted in the boa described herein correspond to the clinical behavior of odontogenic fibromyxoma in human beings and mammals. 7,12 Presumably, this type of neoplasia arises from the connective tissue of the dental papilla. It is highly unusual that the mandibula or maxilla is the site of origin of a true fibromyxoma.…”