Diagnosis and Management of Endometrial Polyps: A Critical Review of the Literature

Salim, S.; Won, H.; Nesbitt‐Hawes, Erin; Campbell, Neil; Abbott, Jason

doi:10.1016/j.jmig.2011.05.018

Cited by 222 publications

(189 citation statements)

References 118 publications

Supporting

Mentioning

159

Contrasting

Unclassified

Order By: Relevance

“…They are detected in 1% to 12% of asymptomatic patients during routine transvaginal sonography investigation [1]. In our clinical practice, we diagnosed endometrial polyps in 32% of women treated for infertility who qualified for in vitro fertilization.…”

Section: Introductionmentioning

confidence: 95%

“…In our clinical practice, we diagnosed endometrial polyps in 32% of women treated for infertility who qualified for in vitro fertilization. The incidence of precancerous and cancerous transformation is low in these polyps [1,2]. According to recent reports, the percentage polyps that are malignant varies from 0.8% to 8% among postmenopausal patients with concomitant abnormal uterine bleeding [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Usefulness of saline infusion sonohysterography and feeding artery imaging in endometrial polyp diagnosis

Anioł

Dec²,

Wojda³

et al. 2017

Ginekol Pol

View full text Add to dashboard Cite

Objectives: The aim of this study was to assess the usefulness of sonohysterography with feeding artery visualization using transvaginal sonography to diagnose endometrial polyps. Material and methods:We conducted an observational study of 60 perimenopausal patients referred to the Department of Fetal Medicine and Gynaecology, Medical University of Lodz with abnormal uterine bleeding or suspicion of endometrial pathology based on sonography scan. In all 60 patients transvaginal sonography scan showed a possibility of an endometrial polyp. Of these, 46 underwent saline infusion sonohysterography with sonography visualization of a feeding artery.Pathological examination was performed on material collected during hysteroscopy.Results: Sonography detection of endometrial polyp based on feeding artery visualization had a 40% sensitivity, whereas sonohysterographic polyp detection had a sensitivity of 75% and a specificity of 100%. The positive and negative predictive values of saline infusion sonohysterography in diagnosing endometrial polyps were estimated at 75% and 72% (95% CI: 52-86%), respectively. The combination of sonohysterography and feeding artery imaging in transvaginal sonography was 84% sensitive and 95% specific in detecting endometrial polyps. The positive and negative predictive values were: PPV = 96% and NPV = 89%. Conclusion:Saline infusion sonohysterography with feeding artery visualization may become a standard method in the diagnostics of endometrial polyps in perimenopausal women.

show abstract

Section: Introductionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Usefulness of saline infusion sonohysterography and feeding artery imaging in endometrial polyp diagnosis

Anioł

Dec²,

Wojda³

et al. 2017

Ginekol Pol

View full text Add to dashboard Cite

show abstract

“…Endometrial polyp (EP) is one of the most common pathology that is associated with AUB or infertility and may be present in both pre and post-menopausal women (Salim et al, 2011). Endometrial hyperplasia (EH) is the abnormal proliferation of the endometrial glands and stroma and related with risk of increased endometrial carcinoma (Li et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Risk Factors for Endometrial Hyperplasia Concomitant Endometrial Polyps in Pre- and Post-menopausal Women

Topçu¹,

Erkaya²,

Güzel³

et al. 2014

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Purpose: To evaluate the risk factors for endometrial hyperplasia concomitant endometrial polyps in preand post-menopausal women. Materials and Methods: A total of 203 patients undergoing endometrial sampling before hysterectomy were evaluated in this retrospective study. Data recorded were age, gravidity, parity, body mass index (BMI: weight(kg)/height(m) 2 ), endometrial thickness (ET), menopausal status, presence of adenomyosis and diabetes mellitus. Results: Endometrial hyperplasia and polyps were detected in 13 patients. There were statistically significant differences in terms of age, menopausal status, morbid obesity and diabetes mellitus (p<0.005). Logistic regression demonstrated that menopausal status and presence of diabetes mellitus were independent risk factors. Conclusions: According to the current study; menopause and diabetes mellitus are strong risk factors for the presence of concomitant endometrial polyps and endometrial hyperplasia.

show abstract

“…Sua prevalência é maior entre mulheres que se encontram na faixa etária dos 40 aos 60 anos, e duas vezes maior entre aquelas na pós-menopausa, comparativamente ao período de menacme 2,4 . São responsáveis por 21 a 28% de todas as causas de sangramento uterino na pós-menopausa, configurando relevante condição para o diagnóstico diferencial da neoplasia endometrial 5,6 . A incidência do câncer de endométrio associado aos pólipos está em torno de 3,5%, variando segundo a maioria dos estudos entre 0,0 e 4,8%, sendo que esse risco é maior em mulheres na pós-menopausa com sangramento 6,7 .…”

Section: Introductionunclassified

“…São responsáveis por 21 a 28% de todas as causas de sangramento uterino na pós-menopausa, configurando relevante condição para o diagnóstico diferencial da neoplasia endometrial 5,6 . A incidência do câncer de endométrio associado aos pólipos está em torno de 3,5%, variando segundo a maioria dos estudos entre 0,0 e 4,8%, sendo que esse risco é maior em mulheres na pós-menopausa com sangramento 6,7 . Como fatores de risco para o desenvolvimento de pólipos endometriais, bem como para degeneração maligna dos mesmos, são considerados idade avançada, nuliparidade, menarca precoce, menopausa tardia, obesidade, diabetes, hipertensão e uso de tamoxifeno 8,9 .…”

Section: Introductionunclassified

Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausa

Bueloni-Dias¹,

Dias²,

Neto³

et al. 2014

Rev. Bras. Ginecol. Obstet.

View full text Add to dashboard Cite

ResumoOBJETIVO: Avaliar os fatores clínicos preditivos para o desenvolvimento dos pólipos endometriais em mulheres na pós-menopausa. MÉTODOS: Estudo de coorte observacional com mulheres na pós-menopausa, que haviam sido atendidas em hospital público universitário. Dados clínicos, antropométricos, laboratoriais e ultrassonográficos de 132 pacientes com diagnóstico anatomopatológico de pólipo endometrial e de 264 mulheres sem alterações endometriais (controle) foram comparados para avaliar os fatores preditivos do pólipo endometrial. Foram incluídas no estudo mulheres com amenorreia ≥12 meses e idade ≥45 anos, em uma proporção de 1 caso para 2 controles. Para a análise estatística, foram empregados os testes t de Student, χ 2 e regressão logística -odds ratio (OR). RESULTADOS: As pacientes com pólipo endometrial apresentaram idade mais avançada e maior tempo de menopausa quando comparadas ao controle (p<0,0001). A porcentagem de mulheres obesas com pólipo (72,0%) foi superior à do Grupo Controle (39%; p<0,0001). A medida da circunferência da cintura foi superior entre as pacientes com pólipo (p=0,0001). Observou-se uma incidência de diabetes, hipertensão e dislipidemias mais elevada nas pacientes com pólipo endometrial (p<0,0001). De acordo com os critérios do US National Cholesterol Education Program/ Adult Treatment Panel III (NCEP/ATP III), 48,5% das mulheres com pólipo e 33,3% do Grupo Controle foram classificadas como portadoras de síndrome metabólica (p=0,004). Em relação ao Grupo Controle, apresentaram maior chance de desenvolvimento de pólipo endometrial as pacientes com: IMC≥25 kg/m 2 (OR=4,6; IC95% 2,1-10,0); glicose ≥100 mg/dL (OR=2,8; IC95% 1,3-5,9); dislipidemia (OR=7,0; IC95% 3,7-13,3); diabetes (OR=2,5; IC95% 1,0-6,3) e síndrome metabólica (OR=2,7; IC95% 1,1-6,4). CONCLUSÃO: Em mulheres na pós-menopausa, obesidade, dislipidemia, hiperglicemia e presença de síndrome metabólica foram fatores preditivos para o desenvolvimento de pólipo endometrial.Abstract PURPOSE: To evaluate the predictive clinical factors for the development of endometrial polyps in postmenopausal women. METHODS: Observational cohort study with postmenopausal women who had been at a public university hospital. Clinical, anthropometrical, laboratorial, and ultrasonographic data of 132 patients with a histopathological diagnosis of endometrial polyps and 264 women without endometrial alterations (control) were compared in order to evaluate the predictive factors of endometrial polyps. Women with amenorrhea ≥12 months and ≥45 years of age were included in the study at a proportion of 1 case for 2 controls. The Student's t-, χ 2 , and logistic regression tests were used for statistical analysis -odds ratio (OR). RESULTS: Patients with endometrial polyps were older and had been in menopause for a longer time compared to control (p<0.0001). The percentage of obese women with polyps (72.0%) was higher compared to the Control Group (39%; p<0.0001). The measurement of waist circumference was superior among patients with polyps

show abstract

Diagnosis and Management of Endometrial Polyps: A Critical Review of the Literature

Cited by 222 publications

References 118 publications

Usefulness of saline infusion sonohysterography and feeding artery imaging in endometrial polyp diagnosis

Usefulness of saline infusion sonohysterography and feeding artery imaging in endometrial polyp diagnosis

Risk Factors for Endometrial Hyperplasia Concomitant Endometrial Polyps in Pre- and Post-menopausal Women

Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausa

Contact Info

Product

Resources

About