Diagnosis and Management of Embryonal Rhabdomyosarcoma in a Woman with Prolapsing Cervical Mass

Connor, Elizabeth V.; DiSilvestro, Paul

doi:10.23937/2377-9004/1410050

Cited by 1 publication

(1 citation statement)

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“…10,11 It is primarily a childhood malignancy and is almost always associated with TP53 mutations and a poor prognostic outcome. 12 The 2008 and 2021 reports from Soft Tissue Sarcoma Committee for the Children's Oncology Group mentioned that embryonal RMS most commonly presented in the 1 st decade of life, with approximately 82% of these cases having TP53 mutations. 10,11 Although rhabdomyosarcoma is considered relatively common among children with vaginal sarcoma, embryonal cervical rhabdomyosarcoma is extremely rare and usually occurs in women in the second and third decades of life.…”

Section: Discussionmentioning

confidence: 99%

Embryonal rhabdomyosarcoma of the uterine cervix in an adult female

Jadhav¹,

Madakshira²,

Garud³

2023

Autops Case Rep

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Embryonal rhabdomyosarcoma (RMS) of the female genital tract is an uncommon malignancy, presenting mainly in the pediatric and adolescent populations, primarily affecting the first two decades of life. This malignancy presentation in adulthood is rare and is seldom seen. The incidence of this tumor affecting adult females is approximately 0.4 -1%, with the common site being the vagina. This tumor infrequently involves the cervix. RMS has a poor survival rate and once diagnosed, it requires aggressive management by radical surgery accompanied by chemoradiation. We present a case of an anaplastic variant of embryonal RMS of the uterine cervix presenting as a cervical polyp in a 36-year-old female who complained of dyspareunia and post-coital bleeding.

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Section: Discussionmentioning

confidence: 99%