Diagnosis and epidemiology of Leishmania infantum in domestic cats in an endemic area of the Amazon region, Brazil

Rocha, Ana Vitória Verde Oliveira; Moreno, Brenda Fernanda Sodré; Cabral, Aline Diniz; Louzeiro, Nayara Mendes; Miranda, Leandro Macedo; Santos, Vivian Magalhães Brandão dos; Costa, Francisco Borges; Nogueira, Rita de Maria Seabra; Marcili, Arlei; Sperança, Márcia Aparecida; Costa, Andréa Pereira da

doi:10.1016/j.vetpar.2019.08.007

Cited by 28 publications

(29 citation statements)

References 55 publications

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“…The presence of pets, such as dogs and/or cats, in residences provides conditions for L. infantum to complete its life cycle in the canine reservoir, with cats serving as accidental hosts. The presence of these pets in residences and the association with the risk of VL development agree with other reports of a higher CVL rate in dogs in contact with other dogs 8,9 and in cats cohabiting with dogs previously affected by VL 27 .…”

Section: Resultssupporting

confidence: 90%

Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area

Rodrigues

Benitez

Sevá

et al. 2020

Rev. Soc. Bras. Med. Trop.

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Introduction: Canine visceral leishmaniasis (CVL) is a public health problem, and its prevalence is associated with the coexistence of vectors and reservoirs. CVL is a protozoonosis caused by Leishmania infantum that is endemic in the southeast region of Brazil. Thus, vector and canine reservoir control strategies are needed to reduce its burden. This study aimed to verify the CVL seroprevalence and epidemiology in a municipality in Southeast Brazil to initiate disease control strategies. Methods: A total of 833 dogs were subjected to Dual Path Platform (DPP) testing and enzyme-linked immunosorbent assays. For seropositive dogs, epidemiological aspects were investigated using a questionnaire and a global position system. The data were submitted to simple logistic regression, kernel estimation, and Bernoulli spatial scan statistical analysis. Results: The overall CVL-confirmed seroprevalence was 16.08%. The 28.93% in the DPP screening test was associated with dogs maintained in backyards with trees, shade, animal and/or bird feces, and contact with other dogs and cats, with sick dogs showing the highest chances of infection (odds ratio, 2.6; 95% confidence interval, 2.38-1.98), especially in residences with elderly people. A spatial analysis identified two hotspot regions and detected two clusters in the study area. Conclusions: Our results demonstrated that residences with elderly people and the presence of trees, shade, feces, and pet dogs and cats increased an individual's risk of developing CVL. The major regions where preventive strategies for leishmaniasis were to be initiated in the endemic area were identified in two clusters.

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Section: Resultssupporting

confidence: 90%

Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area

Rodrigues

Benitez

Sevá

et al. 2020

Rev. Soc. Bras. Med. Trop.

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“…that have been described in epidemiological surveys conducted in Brazil and São Paulo state. Illustrative map based on twenty-four articles published in peer-reviewed scientific journals between 1940 and 2019, and the results from the present study (Benassi et al, 2017;Bresciani, Serrano, Matos, Savani, & D'Auria, 2010;Cardia, Camossi, Neto, Langoni, & Bresciani, 2013;Coelho et al, 2010;Coelho, Richini-Pereira, Langoni, & Bresciani, 2011;Costa et al, 2010;Coura et al, 2018;Figueiredo et al, 2009;Marcondes et al, 2018;Mello, 1940;Mendonça et al, 2017;Metzdorf et al, 2017;Oliveira et al, 2015;Rocha et al, 2019;Savani et al, 2004;Schubach et al, 2004;Sherlock, 1996;Silva, Cândido, Pita-Pereira, Brazil, & Carreira, 2008;Silveira-Neto et al, 2011;Simões-Mattos et al, 2001;Sobrinho et al, 2012;Souza et al, 2005;Souza, Nunes, Borralho, & Ishikawa, 2009;Vides et al, 2011). Map made with the QGIS 2.18 "Las Palmas" software (QGIS Development Team, 2016) using free access datasets from Instituto Brasileiro de Geografia e Estatística [IBGE] (2018) [Colour figure can be viewed at wileyonlinelibrary.com] species present in the city.…”

Section: Re Sults and Discussionmentioning

confidence: 52%

“…seropositive cats can be explained by the high prevalence of CanL in the study area. Moreover, the cohabitation of cats with dogs L. (L.) infantum infected was significantly associated with diagnoses of FL by L. (L.) infantum (Rocha et al, 2019).…”

Section: Re Sults and Discussionmentioning

confidence: 95%

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Leishmaniasis in cat shelters: A serological, molecular and entomological study

Leonel

Vioti

Alves

et al. 2020

Transbound Emerg Dis

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An epidemiological Leishmania spp. and entomological Phlebotomine sandflies survey was performed in cat shelters at leishmaniasis endemic area of Brazil. Blood and conjunctival swab (CS) samples were collected from 94 cats in two animal protection shelters. These samples were subjected to serological tests using the indirect immunofluorescence antibody test (IFAT) and indirect enzyme‐linked immunosorbent assay (ELISA) and to molecular test by polymerase chain reaction (PCR). In addition, a Phlebotomine sandflies survey was performed in the same shelters. The analyses revealed a positivity of 31.91% (30/94) through ELISA and 29.79% (28/94) through IFAT. The two serological tests showed a positive association with perfect agreement (k = 0.925). None of the cats were positive by Leishmania spp. DNA. One Lutzomyia (Lutzomyia) longipalpis male was found in one of the cat shelters. The results and the implications of our findings are discussed below.

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“…A soropositividade elevada encontrada no estudo sugere que esses gatos estão em constante contato com os tripanossomatídeos (MATOS et al, 2018), possivelmente pela coabitação com cães infectados com Leishmania spp. (ROCHA et al, 2019), e pela presença de flebotomíneos vetores que eram atraídos pela matéria orgânica produzida pelos animais.…”

Section: Alterações Clínicas E Diagnósticounclassified

>b<Identificação e caracterização de tripanossomatídeos que infectam gatos domésticos (>i<Felis catus>/i<) de área endêmica para leishmaniose visceral>/b<

Alves¹

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Diagnosis and epidemiology of Leishmania infantum in domestic cats in an endemic area of the Amazon region, Brazil

Cited by 28 publications

References 55 publications

Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area

Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area

Leishmaniasis in cat shelters: A serological, molecular and entomological study

>b<Identificação e caracterização de tripanossomatídeos que infectam gatos domésticos (>i<Felis catus>/i<) de área endêmica para leishmaniose visceral>/b<

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