Diagnosis and correction methods for spectral interference in the framework of LIBS imaging

Duponchel, Ludovic; Cugerone, Alexandre; Muñoz, Manuel; Motto-Ros, Vincent

doi:10.1016/j.sab.2023.106758

Cited by 7 publications

(4 citation statements)

References 21 publications

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“…of Cl. Likewise, diagnosis and spectral correction methods for LIBS imaging were developed by Duponchel et al 118 The authors were able to diagnose the presence of a potential spectral interference and to correct it using PCA and multivariate curve resolution (MCR)-ALS methods, respectively. This method was applied to LIBS imaging dataset obtained from the analysis of a complex rock.…”

Section: Laser Induced Breakdown Spectroscopymentioning

confidence: 99%

“…Sb-doping was also used to constrain the mass bias correction with the lasergenerated aerosol being combined with an Sb aerosol in a wet plasma spray chamber. Repeated analysis estimated that the intermediate precision for d 122 Sn/ 118 Sn was ± 0.12&. Zhang et al 166 took the approach of synthesising a homogenous cassiterite RM.…”

Section: Stable Isotope Ratio Studiesmentioning

confidence: 99%

See 1 more Smart Citation

Atomic spectrometry update: review of advances in atomic spectrometry and related techniques

Evans,

Pisonero,

Smith

et al. 2024

J. Anal. At. Spectrom.

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Section: Laser Induced Breakdown Spectroscopymentioning

confidence: 99%

Section: Stable Isotope Ratio Studiesmentioning

confidence: 99%

Atomic spectrometry update: review of advances in atomic spectrometry and related techniques

Evans,

Pisonero,

Smith

et al. 2024

J. Anal. At. Spectrom.

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show abstract

“…Like any spectroscopy-based imaging technique, the wealth of chemical information contained within a LIBS spectrum quickly necessitated the development of chemometric tools to extract and leverage it . As a result, all the typical multivariate tools in chemometrics (which simultaneously leverage the thousands of wavelengths in a LIBS spectrum), such as exploratory methods, clustering, or signal unmixing, have been applied across various fields and complex sample sets. The vast majority of these approaches are built upon leveraging the variance expressed in the spectral data set.…”

Section: Introductionmentioning

confidence: 99%

Enhancing Diagnostic Capabilities for Occupational Lung Diseases Using LIBS Imaging on Biopsy Tissue

Ferreira,

Gardette,

Busser

et al. 2024

Anal. Chem.

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Laser-induced breakdown spectroscopy (LIBS) imaging continues to gain strength as an influential bioanalytical technique, showing intriguing potential in the field of clinical analysis. This is because hyperspectral LIBS imaging allows for rapid, comprehensive elemental analysis, covering elements from major to trace levels consistently year after year. In this study, we estimated the potential of a multivariate spectral data treatment approach based on a so-called convex envelope method to detect exotic elements (whether they are minor or in trace amounts) in biopsy tissues of patients with occupational exposure-related diseases. More precisely, we have developed an approach called Interesting Features Finder (IFF), which initially allowed us to identify unexpected elements without any preconceptions, considering only the set of spectra contained in a LIBS hyperspectral data cube. This task is, in fact, almost impossible with conventional chemometric tools, as it entails identifying a few exotic spectra among several hundred thousand others. Once this detection was performed, a second approach based on correlation was used to locate their distribution in the biopsies. Through this unique data analysis pipeline to processing massive LIBS spectroscopic data, it was possible to detect and locate exotic elements such as tin and rhodium in a patient's tissue section, ultimately leading to a possible reclassification of their lung condition as an occupational disease. This review will thus demonstrate the potential of this new diagnostic tool based on LIBS imaging in addressing the shortcomings of approaches developed thus far. The proposed data processing approach naturally transcends this specific framework and can be leveraged across various domains of analytical chemistry, where the detection of rare events is concealed within extensive data sets.

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“…23,24 However, the LIBS technique faces several critical challenges due to the complex of the spatial-temporal evolution of plasma. These challenges include matrix effects, 25 spectral interference, [26][27][28] and self-absorption 29 which hinders the further development and application of this technology. Compared to traditional elemental analysis technologies such as inductively coupled plasma-mass spectrometry (ICP-MS), 16 X-ray fluorescence spectrometry (XRF), 17 and electron probe micro-analysis (EPMA), 18 LIBS still exhibits lower accuracy in quantitative analysis, primarily due to the self-absorption effect.…”

Section: Introductionmentioning

confidence: 99%

A Review Of Development In The Research Of Self-Absorption On Laser-Induced Breakdown Spectroscopy

Tang,

Zhao

2024

At.Spectrosc.

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Diagnosis and correction methods for spectral interference in the framework of LIBS imaging

Cited by 7 publications

References 21 publications

Atomic spectrometry update: review of advances in atomic spectrometry and related techniques

Atomic spectrometry update: review of advances in atomic spectrometry and related techniques

Enhancing Diagnostic Capabilities for Occupational Lung Diseases Using LIBS Imaging on Biopsy Tissue

A Review Of Development In The Research Of Self-Absorption On Laser-Induced Breakdown Spectroscopy

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