Diagnosing phyllodes tumours of the breast: how successful are our current preoperative assessment modalities?

Yii, Nathan; Read, Tavis; Tan, Chuan Chien; Ng, Suat Li; Bennett, Ian C.

doi:10.1111/ans.14815

Cited by 7 publications

(5 citation statements)

References 21 publications

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“…However, PTs disturb the balance, with overgrowth of stroma, resulting in a leaf-shaped appearance. According to the World Health Organization, PTs are classified as benign, borderline, and malignant based on five factors: the cellular pleomorphism, degree of mitosis, overgrowth of the stroma, appearance of the margin, and distribution of stoma [ 4 ]. Local recurrence can occur in all subtypes of PTs.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound-guided vacuum-assisted excisional biopsy to treat benign phyllodes tumors

Shang

Zhang

et al. 2020

The Breast

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Purpose To evaluate the value of ultrasound (US)-guided vacuum-assisted excisional biopsy (VAB) in treating benign phyllodes tumors (PTs) of the breasts and to investigate the lesion characteristics that could affect the local recurrence rate. Patient and methods From December 2008 to February 2018, 93 patients with PTs diagnosed on histology underwent US-guided, 7-gauge VAB. The recurrence rate of benign PT and complications of VAB were evaluated on follow-up US every three to six months. The lesion characteristics were analyzed to identify the factors affecting the recurrence rate. Results Of the 87 patients, local recurrence was found in 15 patients (17%) in a mean follow-up period of 35.8 months, and the rate of complete excision was 82.8% (72/87). PTs with a largest diameter less than 3.3 cm had a significantly lower recurrence rate than PTs with a largest diameter larger than 3.3 cm (P < 0.05). Conclusions In conclusion, US-guided VAB is an effective method to treat benign PT, especially in lesions with a diameter less than 3.3 cm.

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Section: Introductionmentioning

confidence: 99%

Ultrasound-guided vacuum-assisted excisional biopsy to treat benign phyllodes tumors

Shang

Zhang

et al. 2020

The Breast

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“…This is in agreement with a previous study which found that mean lesion size increased when comparing benign, borderline and malignant phyllodes tumours. (18) However, this study did not include any fibroadenomas.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have compared the imaging features of fibroadenomas and phyllodes tumours (1,16,17) but none has compared the imaging features of those lesions requiring excision with a margin and those which do not. (18) In this study, we aimed to identify ultrasound and mammographic features associated with borderline and malignant phyllodes versus benign phyllodes and fibroadenomas to aid surgical planning. Attention was paid to features previously described to be suggestive of a phyllodes tumour.…”

Section: Introductionmentioning

confidence: 99%

Preoperative prediction of margin requirement following a core biopsy result suggestive of a phyllodes tumour

et al. 2020

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“…Diagnosed as malignant phyllodes tumor. When the phyllodes tumor does not have all the malignant histological characteristics of malignant phyllodes tumors, then it is diagnosed as a benign phyllodes tumor ( 5 , 6 ).…”

Section: Introductionmentioning

confidence: 99%

The treatment process of an extremely rare giant borderline phyllodes tumor of breast: case report and literature review

Wang¹,

Zheng²,

Zhang³

et al. 2021

Transl Cancer Res TCR

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Giant phyllodes tumors are rare fibroepithelial neoplasms, usually defined as >10 cm. It is often difficult for pathologists to distinguish fibroadenomas from phyllodes tumors and determine the malignant potential level. The current treatment principle is to ensure the extended resection of tumors with a margin of 1 cm or more. For patients with multiple local recurrences or large tumors after surgery, simple mastectomy is recommended. Axillary management should be considered when breast cancer is diagnosed at the same time. We now present a rare case: a female patient found a right breast mass in 2014, and the mass had continued to grow for more than 7 months, and she was ultimately diagnosed with a giant phyllodes tumor with a diameter of 30 cm. Extensive resection is a suitable method to treat smaller phyllodes tumors, but giant phyllodes tumors require mastectomy, so the patient in this case underwent a total mastectomy. We removed the mass completely without destroying the normal tissue and structure. The treatment effect was obvious, and no related adverse events occurred during or after the operation, the postoperative recovery was good, and the patient was discharged once she was verified to be in a stable condition. This case is the first reported case of a patient who had a giant borderline phyllodes tumor with a diameter of 30 cm, underwent total mastectomy, and was followed up for 6 months without recurrence. The long-term effect of the treatment will be further evaluated after 5 years.

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Diagnosing phyllodes tumours of the breast: how successful are our current preoperative assessment modalities?

Cited by 7 publications

References 21 publications

Ultrasound-guided vacuum-assisted excisional biopsy to treat benign phyllodes tumors

Ultrasound-guided vacuum-assisted excisional biopsy to treat benign phyllodes tumors

Preoperative prediction of margin requirement following a core biopsy result suggestive of a phyllodes tumour

The treatment process of an extremely rare giant borderline phyllodes tumor of breast: case report and literature review

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