Diagnosing Disconnected Pancreatic Duct Syndrome: Many Disconnects, Few Answers

Vaněk, Petr; Trikudanathan, Guru; Freeman, Martin L.

doi:10.1007/s10620-020-06538-2

Cited by 8 publications

(5 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Disruption or DPDS is a potential complication of WON. Roughly 30-50% of patients with pancreatic necrosis may experience DPDS and are more likely to require additional therapeutic interventions, rescue surgery and/or an extended hospital stay [ 73 , 74 ].…”

Section: Management Of Disconnected Pancreatic Duct Syndrome (Dpds)mentioning

confidence: 99%

Endoscopic management of pancreatic walled-off necrosis

Ramai¹

2023

aog

View full text Add to dashboard Cite

Pancreatic walled-off necrosis (WON) is a complication of severe pancreatitis. Endoscopic transmural drainage has been recognized as the first-line treatment for pancreatic fluid collections. Endoscopy offers a minimally invasive approach when compared to surgical drainage. Today, endoscopists may choose to use self-expanding metal stents, pigtail stents, or lumen-apposing metal stents to facilitate drainage of fluid collections. Current data suggest that all 3 approaches yield similar outcomes. It was previously thought that drainage should be performed 4 weeks from the initial event of pancreatitis, theoretically allowing the capsule to mature. However, current data show that both early (<4 weeks) and standard (≥4 weeks) endoscopic drainage are comparable. Herein, we provide an up-to-date state-of-the-art review of the indications, techniques, innovations, outcomes, and future perspectives following drainage of pancreatic WON.

show abstract

Section: Management Of Disconnected Pancreatic Duct Syndrome (Dpds)mentioning

confidence: 99%

Endoscopic management of pancreatic walled-off necrosis

Ramai¹

2023

aog

View full text Add to dashboard Cite

show abstract

“…155 In some studies, the prevalence of DDS has been reported in as many as 30% to 50% of cases of necrotizing pancreatitis. 157 The frequency of DDS and its potential to be a major complication should prompt further study regarding the utility of excluding it in all patients with necrotizing pancreatitis.…”

Section: Disconnected Duct Syndromementioning

confidence: 99%

Management of Pancreatic Fluid Collections

Sameera

Mohammad

Liao

et al. 2022

Journal of Clinical Gastroenterology

View full text Add to dashboard Cite

Managing pancreatic fluid collections (PFCs) remains a challenge for many clinicians. Recently, significant progress has been made in the therapy of PFCs, including improvements in technology and devices, as well as in the development of minimally invasive endoscopic techniques, many of which are proven less traumatic when compared with surgical options and more efficacious when compared with percutaneous techniques. This review will explore latest developments in the management of PFCs and how they incorporate into the current treatment algorithm.

show abstract

“…[ 19 ] DPDS refers to a clinical condition caused by the symptomatic production of pancreatic juice due to ductal discontinuity between viable pancreatic tissue and the duodenum. [ 20 ] The correct differentiation between them contributes to different management decision-making. [ 20 ] It is unnecessary to aggressively look for PD disruptions or disconnections because whether a patient with NP will develop DPDS or not is generally unclear in the first 2 weeks.…”

Section: Diagnosismentioning

confidence: 99%

“…[ 20 ] The correct differentiation between them contributes to different management decision-making. [ 20 ] It is unnecessary to aggressively look for PD disruptions or disconnections because whether a patient with NP will develop DPDS or not is generally unclear in the first 2 weeks. [ 11 ] Furthermore, the initial treatment of NP focuses on other aspects.…”

Section: Diagnosismentioning

confidence: 99%

Endoscopic management of pancreatic fluid collections with disconnected pancreatic duct syndrome

Wang

Song

et al. 2022

Endoscopic Ultrasound

View full text Add to dashboard Cite

Disconnected pancreatic duct syndrome (DPDS) is an important and common complication of acute necrotizing pancreatitis. Endoscopic approach has been established as the first-line treatment for pancreatic fluid collections (PFCs) with less invasion and satisfactory outcome. However, the presence of DPDS significantly complicates the management of PFC; besides, there is no standardized treatment for DPDS. The diagnosis of DPDS presents the first step of management, which can be preliminarily established by imaging methods including contrast-enhanced computed tomography, ERCP, magnetic resonance cholangiopancreatography (MRCP), and EUS. Historically, ERCP is considered as the gold standard for the diagnosis of DPDS, and secretin-enhanced MRCP is recommended as an appropriate diagnostic method in existing guidelines. With the development of endoscopic techniques and accessories, the endoscopic approach, mainly including transpapillary and transmural drainage, has been developed as the preferred treatment over percutaneous drainage and surgery for the management of PFC with DPDS. Many studies concerning various endoscopic treatment strategies have been published, especially in the recent 5 years. Nonetheless, existing current literature has reported inconsistent and confusing results. In this article, the latest evidence is summarized to explore the optimal endoscopic management of PFC with DPDS.

show abstract

Diagnosing Disconnected Pancreatic Duct Syndrome: Many Disconnects, Few Answers

Cited by 8 publications

References 11 publications

Endoscopic management of pancreatic walled-off necrosis

Endoscopic management of pancreatic walled-off necrosis

Management of Pancreatic Fluid Collections

Endoscopic management of pancreatic fluid collections with disconnected pancreatic duct syndrome

Contact Info

Product

Resources

About