Diagnosing autism in a clinical sample of adults with intellectual disabilities: How useful are the ADOS and the ADI-R?

Sappok, Tanja; Diefenbacher, Albert; Budczies, Jan; Schade, Christoph; Grubich, Claudia; Bergmann, Thomas; Bölte, Sven; Dziobek, Isabel

doi:10.1016/j.ridd.2013.01.028

Cited by 73 publications

(55 citation statements)

References 56 publications

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“…The majority of these items pertained to the social interaction domain (9 out of 15 in total) rather than to the communication domain (5 out of 14 in total), suggesting that items representing social interaction yielded better discriminative diagnostic validity. Similar findings were gained in previous research [Brooks & Benson, ; Sappok et al, ] and are also consistent with the notion that difficulties with verbal communication can present a significant challenge for individuals with ID [Tuffrey‐Wijne & McEnhill, ] and people with ASD (Association, 2013). Consequently, items related to verbal communication may not distinguish between these groups well.…”

Section: Discussionsupporting

confidence: 90%

The Social Communication Questionnaire for adults with intellectual disability: SCQ‐AID

Derks

Heinrich

Brooks³

et al. 2017

Autism Research

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Autism spectrum disorder (ASD) frequently co-occurs with intellectual disability (ID) and often remains undiagnosed until adulthood. The Social Communication Questionnaire (SCQ) is a widely used measure to screen for ASD. To improve the utility of the SCQ for adults with ID, the aim of this study was to develop an ID-specific and adult appropriate algorithm for the SCQ using a core set of valid items. These items were identified in one sample (N = 226) and further cross-validated in a second, independent sample (N = 225) from Germany, England and the U.S. The newly developed algorithm has 24 items compared with the 40 items in the original instrument. The reduced item core set yielded similar diagnostic validity as the original algorithm with good sensitivity values (0.81-0.89) and low specificity values (0.62-0.72). Overall, these results suggest that the removed items may not carry diagnostically relevant information in adults with ID; thus, excluding these items may result in a more efficient and age-appropriate screening measure for this population. However, due to the low specificity values, a comprehensive assessment is essential for a final diagnostic assignment. Autism Res 2017, 10: 1481-1490. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.

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Section: Discussionsupporting

confidence: 90%

The Social Communication Questionnaire for adults with intellectual disability: SCQ‐AID

Derks

Heinrich

Brooks³

et al. 2017

Autism Research

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“…Furthermore, other studies have also found the individual’s intellectual ability may have undue influence on the ADI-R, with higher false positive rates when used to assess individuals with intellectual disability (ID; Lord et al 1997). However, other studies have reported adequate sensitivity and specificity of the ADI-R in identifying ASD in children and adults with ID (de Bildt et al 2005; Sappok et al 2013). …”

Section: Validity Of the Adi-rmentioning

confidence: 93%

Clinical Validity of the ADI-R in a US-Based Latino Population

Vanegas

Magaña

Morales

et al. 2016

J Autism Dev Disord

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The Autism Diagnostic Interview-Revised has been validated as a tool to aid in the diagnosis of Autism; however, given the growing diversity in the United States, the ADI-R must be validated for different languages and cultures. This study evaluates the validity of the ADI-R in a U.S.-based Latino, Spanish-speaking population of 50 children and adolescents with ASD and developmental disability. Sensitivity and specificity of the ADI-R as a diagnostic tool were moderate, but lower than previously reported values. Validity of the social reciprocity and restrictive and repetitive behaviors domains was high, but low in the communication domain. Findings suggest that language discordance between caregiver and child may influence reporting of communication symptoms and contribute to lower sensitivity and specificity.

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“…) may also be used in adults with ID (Sappok et al . ). The Music Based Assessment for Autism‐spectrum‐Disorders (MUSAD) is a newly developed interactive tool specifically designed for adults with ID who are suspected of having ASD (Bergmann et al .…”

Section: Introductionmentioning

confidence: 97%

Screening for ASD in adults with ID—moving toward a standard using the DiBAS‐R and the ACL

Mutsaerts

Heinrich

Sterkenburg

et al. 2016

J intellect Disabil Res

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Diagnosing autism in a clinical sample of adults with intellectual disabilities: How useful are the ADOS and the ADI-R?

Cited by 73 publications

References 56 publications

The Social Communication Questionnaire for adults with intellectual disability: SCQ‐AID

The Social Communication Questionnaire for adults with intellectual disability: SCQ‐AID

Clinical Validity of the ADI-R in a US-Based Latino Population

Screening for ASD in adults with ID—moving toward a standard using the DiBAS‐R and the ACL

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