Diagnosing acute kidney injury ahead of time in critically ill septic patients using kinetic estimated glomerular filtration rate

LIJOVIC, Lada; Pelajić, Stipe; Hawchar, Fatime; Minev, Ivaylo; Silva, Beatriz Helena Cermaria Soares da; Angelucci, Alessandra; Ercole, Ari; Grooth, Harm-Jan de; Thoral, Patrick; Radocaj, Tomislav; Elbers, Paul

doi:10.1016/j.jcrc.2023.154276

Cited by 3 publications

(2 citation statements)

References 33 publications

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“…We see that the KeGFR allows a faster diagnosis of AKI using serial creatinine determinations at time intervals and with good ability to predict the severity of AKI, with the ability to predict the need for KRT and mortality. It is possible that the use of KeGFR, FST, and biomarkers provides complementary tools for the early diagnosis of AKI and allows better decisions to be made in choosing the right moment to start KRT (Figure 7) [138].…”

Section: Kinetic Efgmentioning

confidence: 99%

Timing of Initiation of Kidney Replacement Therapy in Acute Kidney Injury in the Critically Ill Patient

Alejandro Tavera Diaz

2024

Updates on Renal Replacement Therapy

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Acute kidney injury (AKI) represents one of the most frequent complications in critically ill patients. In recent years, mortality rates have exceeded 50%, and 10% of them require kidney replacement therapy (KRT). Since the 60’s, the question of when to start KRT has been raised, classically the time of temporality when life-threatening (hyperkalemia, metabolic acidosis, uremia, and fluid overload); in the last decade, the possibility of early initiation was raised as a strategy to achieve better outcomes. Current evidence shows that the timing of late onset has the same results as the strategy of early onset. We will also review the considerations in relation to renal capacity and demand generated by the acute pathology in a critically ill patient and the set of variables to make better decisions.

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Section: Kinetic Efgmentioning

confidence: 99%

Timing of Initiation of Kidney Replacement Therapy in Acute Kidney Injury in the Critically Ill Patient

Alejandro Tavera Diaz

2024

Updates on Renal Replacement Therapy

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“…As well as attracting skills from other timezones and continents, the online format allowed the datathon to be held over the course of multiple weeks with review presentations along the way. Working remotely and using agile 'sprint' methodologies, this allowed teams of data scientists and intensive care professionals to make more progress and come up with astonishing achievements: the first two virtual datathons have already resulted in four peerreviewed publications [5][6][7][8].…”

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confidence: 99%