Diacylglycerols

Flickinger, B. D.; Matsuo, N.

doi:10.1002/047167849x.bio069

Cited by 4 publications

(3 citation statements)

References 33 publications

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“…Adipose tissue was simulated using refined lard, a ubiquitous cooking product composed almost entirely of triglycerides. As human adipose tissue is composed of more than 90% triglycerides, refined lard, which is also composed of triglycerides to a great extent, provides a good equivalent for human adipose tissue . To simulate connective and epithelial breast tissues, we used egg white that contained similar amounts of water and protein components.…”

Section: Methodsmentioning

confidence: 99%

Accuracy of fully automated, quantitative, volumetric measurement of the amount of fibroglandular breast tissue using MRI: correlation with anthropomorphic breast phantoms

et al. 2017

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To demonstrate the accuracy of fully automated, quantitative, volumetric measurement of the amount of fibroglandular breast tissue (FGT), using MRI, and to investigate the impact of different MRI sequences using anthropomorphic breast phantoms as the ground truth. In this study, 10 anthropomorphic breast phantoms that consisted of different known fractions of adipose and protein tissue, which closely resembled normal breast parenchyma, were developed. Anthropomorphic breast phantoms were imaged with a 1.5 T unit (Siemens, Avantofit) using an 18-channel breast coil. The sequence protocol consisted of an isotropic Dixon sequence (Di), an anisotropic Dixon sequence (Da), and T 3D FLASH sequences with and without fat saturation (T1). Fully automated, quantitative, volumetric measurement of FGT for all anthropomorphic phantoms and sequences was performed and correlated with the amounts of fatty and protein components in the phantoms as the ground truth. Fully automated, quantitative, volumetric measurements of FGT with MRI for all sequences ranged from 5.86 to 61.05% (mean 33.36%). The isotropic Dixon sequence yielded the highest accuracy (median 0.51%-0.78%) and precision (median range 0.19%) compared with anisotropic Dixon (median 1.92%-2.09%; median range 0.55%) and T -weighted sequences (median 2.54%-2.46%; median range 0.82%). All sequences yielded good correlation with the FGT content of the anthropomorphic phantoms. The best correlation of FGT measurements was identified for Dixon sequences (Di, R = 0.999; Da, R = 0.998) compared with conventional T -weighted sequences (R = 0.971). MRI yields accurate, fully automated, quantitative, volumetric measurements of FGT, an increasingly important and sensitive imaging biomarker for breast cancer risk. Compared with conventional T sequences, Dixon-type sequences show the highest correlation and reproducibility for automated, quantitative, volumetric FGT measurements using anthropomorphic breast phantoms as the ground truth.

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Section: Methodsmentioning

confidence: 99%

Accuracy of fully automated, quantitative, volumetric measurement of the amount of fibroglandular breast tissue using MRI: correlation with anthropomorphic breast phantoms

et al. 2017

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“…The health effects of 1,3-DAGs are primarily due to their different acylglycerol structure and metabolic characteristics compared to TAGs (Yanai et al, 2007). Obviously, 1,3-DAGs are digested without the formation of 2-MAGs, and therefore, the re-synthesis of TAGs via 2-MAG pathway can be inhibited (Flickinger & Matsuo, 2005;Phuah et al, 2015).…”

Section: Nutrition Of Conventional Slsmentioning

confidence: 99%

Synthesis, physicochemical properties, and health aspects of structured lipids: A review

Guo

Cai

Xie

et al. 2020

Comp Rev Food Sci Food Safe

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Structured lipids (SLs) refer to a new type of functional lipids obtained by chemically, enzymatically, or genetically modifying the composition and/or distribution of fatty acids in the glycerol backbone. Due to the unique physicochemical characteristics and health benefits of SLs (for example, calorie reduction, immune function improvement, and reduction in serum triacylglycerols), there is increasing interest in the research and application of novel SLs in the food industry. The chemical structures and molecular architectures of SLs define mainly their physicochemical properties and nutritional values, which are also affected by the processing conditions. In this regard, this holistic review provides coverage of the latest developments and applications of SLs in terms of synthesis strategies, physicochemical properties, health aspects, and potential food applications. Enzymatic synthesis of SLs particularly with immobilized lipases is presented with a short introduction to the genetic engineering approach. Some physical features such as solid fat content, crystallization and melting behavior, rheology and interfacial properties, as well as oxidative stability are discussed as influenced by chemical structures and processing conditions. Health‐related considerations of SLs including their metabolic characteristics, biopolymer‐based lipid digestion modulation, and oleogelation of liquid oils are also explored. Finally, potential food applications of SLs are shortly introduced. Major challenges and future trends in the industrial production of SLs, physicochemical properties, and digestion behavior of SLs in complex food systems, as well as further exploration of SL‐based oleogels and their food application are also discussed.

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“…Crude vegetable oils are mainly composed of triacylglycerols (TAGs), but the diacylglycerol (DAG) content can exceed 10% being that in some edible oils as cottonseed, rice bran, and palm oils, the amount can exceed 5%. The monoacylglycerol (MAG) composition is lower and does not exceed 0.2% in edible oils. , …”

Section: Introductionmentioning

confidence: 99%

Liquid–Liquid Equilibrium Data for Systems Involving Triacylglycerols from (Soybean, Cottonseed, or Rice Bran) Oil + Partial Acylglycerols + Anhydrous Ethanol at T = 303.2 and 318.2 K

et al. 2019

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Considering vegetable oils as complex multicomponent mixtures composed of triacylglycerols (TAGs), diacylglycerols (DAGs), and monoacylglycerols (MAGs) in liquid−liquid extraction, as deacidification or another purification technique, it is crucial not only to describe the process, but also the oil enrichment in DAG content, or the obtainment of MAG-rich products, as emulsifiers. This study aimed to attain the liquid−liquid equilibrium (LLE) data of systems composed of TAG of refined oils (soybean, cottonseed, and rice bran) + DAG + MAG + ethanol at T = 303.2 and 318.2 K. The components presented in the liquid phases in equilibrium (TAG, DAG, MAG, and ethanol) were quantified by high-performance size-exclusion chromatography (HPSEC). The preference of DAG for the oil-rich phase and of MAG to the solvent-rich phase is consistent to data reported in the literature. The average deviation between experimental and calculated compositions was less than 0.57% using the NRTL model and up to 6.21% using the original version of the UNIFAC model with two parameters set.

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Diacylglycerols

Cited by 4 publications

References 33 publications

Accuracy of fully automated, quantitative, volumetric measurement of the amount of fibroglandular breast tissue using MRI: correlation with anthropomorphic breast phantoms

Accuracy of fully automated, quantitative, volumetric measurement of the amount of fibroglandular breast tissue using MRI: correlation with anthropomorphic breast phantoms

Synthesis, physicochemical properties, and health aspects of structured lipids: A review

Liquid–Liquid Equilibrium Data for Systems Involving Triacylglycerols from (Soybean, Cottonseed, or Rice Bran) Oil + Partial Acylglycerols + Anhydrous Ethanol at T = 303.2 and 318.2 K

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