Diabetic peripheral neuropathy: Correlation between nerve cross-sectional area on ultrasound and clinical features

Abstract

US is a sensitive diagnostic technique for detecting DPN; however, it does not indicate disease severity.

Diagnostic Ultrasound of the Vagus Nerve in Patients with Diabetes

“…Our result seems conflicting with previous studies that have demonstrated peripheral nerve enlargement in patients with diabetic peripheral neuropathy . We do not have an exact explanation for this but may be peripheral nerve neuropathy and cranial nerve neuropathy have different pathogenesis.…”

“…It had been validated in cases of entrapment neuropathies and recently has been investigated in more generalized neuromuscular disorders . Of interest, enlargement of peripheral nerves has been noted in some studies in patients with diabetes . A logical next step is to investigate its role in the evaluation of the cranial nerves.…”

[Retracted] Applicability of High‐Frequency Ultrasound to the Early Diagnosis of Diabetic Peripheral Neuropathy

“…With advances in ultrasound technology in recent years including probes with higher frequency and better resolution, it has become possible to visualize internal structures such as the epineurium, perineurium, and nerve bundles with a diameter of ≤0.5 mm as well as some small nerves and cutaneous nerves. Thus, HFU provides valuable morphologic information that can complement electrophysiologic data [7,8].…”

Diffusion tensor imaging MR neurography for the detection of polyneuropathy in type 1 diabetes

“…Watanabe et al evaluated the feasibility of CSA at the wrist of 30 DPN vs. 32 healthy controls and found a strong ICC reliability of interobserver (0.998) and intraobserver (0.995) examinations . However, for diagnostic accuracy, studies have shown that nerve ultrasound is unable to distinguish between varying severities of DPN …”