Diabetic mastopathy mimicking breast cancer

Murakami, Ryusuke; Kumita, Shin‐ichiro; Yamaguchi, Kaori; Ueda, Tatsuo

doi:10.1016/j.clinimag.2008.12.003

Cited by 14 publications

(20 citation statements)

References 13 publications

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“…Typically, the lesion results in a hypoechoic formation, more or less irregular contours responsible for a marked attenuation of ultrasound [4,8,10]. These anomalies ultrasound were found in our patient.…”

supporting

confidence: 54%

“…More rarely same anatomical lesions have been described in other autoimmune diseases (thyroiditis, lupus) or diabetes type II insulin requiring [1,7]. Bilaterality is found in about 63% of cases [8]. Male involvement is exceptionally, 5 cases have been reported in diabetic men [6,7].…”

Section: Discussionmentioning

confidence: 94%

“…Hyperglycemia is thought to be the cause of an accumulation of abnormal and decreased conjunctiva tissue degradation in the extracellular matrix [2,3,8].…”

mentioning

confidence: 99%

“…• Many authors [3,7,8] evoke the hypothesis of a immune reaction, secondary to excess glycosylation, involving lymphocyte B cells and macrophages; the presence of cytokines would accentuate the Collagenization phenomenon. The presence of mast cells could promote the secretion of collagen VIII.…”

mentioning

confidence: 99%

“…Radiological examinations provide little information; so the mammograms show frequently overdensities, opacities more or less regular, even dense breasts but without architectural distortion or micro calcification foci [7,8].…”

mentioning

confidence: 99%

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Diabetic Mastopathy, Diagnoses and Management

Ragmoun¹,

Ajili²,

Daadoucha³

2017

J Cytol Histol

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Diabetic mastopathy (DM) is a pathological entity of recent description, it is rare and benign; occurring in young patients with type I diabetes, or having an autoimmune disease. Clinically, she simulates breast cancer. Radiological examinations are not very informative. The diagnosis of certainty is histological. Through an observation of (DM) occurred in a diabetic patient, under insulin for 14 years and carrying multiple degenerative complications, we recall the clinical aspects, radiological and evolutionary of this affection.

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supporting

confidence: 54%

Section: Discussionmentioning

confidence: 94%

“…Hyperglycemia is thought to be the cause of an accumulation of abnormal and decreased conjunctiva tissue degradation in the extracellular matrix [2,3,8].…”

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Diabetic Mastopathy, Diagnoses and Management

Ragmoun¹,

Ajili²,

Daadoucha³

2017

J Cytol Histol

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Clinical Breast Problems and Unusual Breast Conditions

2011

Breast Imaging

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The female breast and diabetes

2011

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The present review outlines the various issues of breast pathology in diabetes. Diabetic mastopathy is an uncommon proliferation of fibrous tissue in the breast that mimics tumour. Breast arterial calcifications represent calcium deposits in the media of arterioles and are more frequently detected on mammograms of diabetic subjects. Importantly, type 2 diabetes mellitus (T2DM) has been associated with breast cancer, but the mechanism underlying this association is complex, since the two entities frequently co-exist and seem to share common aetiological factors and pathways. Furthermore, diabetes has been suggested to negatively affect breast cancer outcomes, but it is unclear whether better glycaemic control would ameliorate prognosis. Preliminary data suggest that antidiabetic treatment may also influence both the incidence and prognosis of breast cancer. However, available evidence is inconclusive and further research is needed. Therefore, treatment of diabetes should not be determined by its potential effect on breast cancer.

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Diabetic mastopathy mimicking breast cancer

Cited by 14 publications

References 13 publications

Diabetic Mastopathy, Diagnoses and Management

Diabetic Mastopathy, Diagnoses and Management

Clinical Breast Problems and Unusual Breast Conditions

The female breast and diabetes

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