Diabetic Ketoacidosis Associated with Recurrent Pulmonary Edema and Rhabdomyolysis in a Patient with Turner's Syndrome.

Abstract

Turner's syndromeis a condition involving total or partial absence of one X chromosomeand has been associated with a number of diseases including non insulin dependent diabetes mellitus, abnormalities of glucose metabolism and hypothreosis. There have been manycase reports in which Turner's syndrome is associated with type 2 diabetes, but the association with type 1 diabetes and/or life threatening complications is very rare. Wepresent an unusual case of a patient with Turner's syndrome whohas type 1 diabetes and is complicated with ketoaddosis, severe acute and recurrent pulmonary edema and rhabdomyolysis. (Internal Medicine 40: 418-420, 2001)

Risk Factors for Coronary Artery Disease among Individuals with Rare Syndrome Intellectual Disabilities

“…Noninsulin dependent diabetes, and less commonly insulin dependent diabetes, is associated with Turner's syndrome. This syndrome has many associated autoimmune diseases and it is not clear whether or not insulin resistance, via an autoimmune function, is the main reason for the increased prevalence for diabetes (Conway, 2002; Gonc, Ozon, Alikasifoglu, & Kandemir, 2002; Gravholt, 2001; Terano et al, 2001). Klinefelter syndrome is another sex chromosome abnormality associated with ID and diabetes in which the mechanism is also thought to be due to insulin resistance.…”