Diabetic Glomerulosclerosis Associated with Renal Microscopic Polyangeitis

An Elderly Patient with Diabetic Nephropathy Complicated by ANCA-associated Nephritis

“…To date, there have been 9 reported cases of diabetic nephropathy complicated by nephritis and associated with anti-neutrophil cytoplasmic antibodies (ANCAs) (2)(3)(4)(5)(6)(7)(8)(9), including the present case, but only 3 of these cases have shown pathological evidence of diabetic nephropathy. The present case is a rare case of nephropathy in which pathological examination proved the co-existence of ANCAassociated nephritis and diabetic nephropathy.…”

Pauci-immune Crescentic Glomerulonephritis Superimposed on Diabetic Glomerulosclerosis

“…Rapidly progressive glomerulonephritis is a common pattern of ARF in older patients coming to renal biopsy. Nevertheless, pauci-immune necrotizing and crescentic glomerulonephritis (PNCGN) superimposed on DGS is a rare occurrence, with only 9 cases reported in the English literature (5)(6)(7)(8)(9)(10)(11)(12). Herein, we describe the clinical, pathologic, and outcome data of 23 patients with PNCGN superimposed on DGS.…”

Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis in Type II Diabetes Mellitus

“…Although myeloperoxidase (MPO)-ANCA was reported to be positive in 38% of patients with type I diabetes mellitus but in 5.7% of healthy subjects (10), it was rarely detected in patients with type II diabetes mellitus. Only nine patients with both ANCA-associated glomerulonephritis and type II diabetic mellitus were previously reported (9,(11)(12)(13)(14)(15)(16)(17)(18). Their mean age was 68.4 years old (range, 50-88), and the ANCA pattern was the perinuclear type in all of them ( Table 2).…”