Diabetic Foot scientific activities in Endocrinology and Metabolism Research Institute

Aalaa, Maryam; Sanjari, Mahnaz; Esfahani, Ensieh Nasli; Atlasi, Rash; Larijani, Bagher; Mohajeri-Tehrani, Mohammad Reza; Mehrdad, Neda; Amini, Mohammad Reza

doi:10.1007/s40200-021-00823-1

Cited by 5 publications

(3 citation statements)

References 22 publications

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“…This disease often affects large and small blood vessels as well as peripheral nerves, resulting in long-term damage, functional impairments, and failure of different organs including the eyes, kidneys, nerves, and blood vessels [2,3]. These effects result in conditions such as retinopathy, renal failure [4], diabetic foot [5], diabetic neuropathy [6], and diabetic osteopathy [7], which significantly impact an individual's health and quality of life. According to the 2021 Global Diabetes Map data released by the International Diabetes Federation, the global prevalence rate of DM among the 20-79-yearold age group was approximately 10.5% (536.6 million people) in 2021, and it is estimated that the rate will increase to approximately 12.2% (783.2 million people) by 2045 [8].…”

Section: Introductionmentioning

confidence: 99%

Nourishing Yin traditional Chinese medicine: potential role in the prevention and treatment of type 2 diabetes

Dai

2024

Am J Transl Res

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Type 2 diabetes mellitus (T2DM), a common and frequently occurring disease in contemporary society, has become a global health threat. However, current mainstream methods of prevention and treatment, mainly including oral hypoglycemic drugs and insulin injections, do not fundamentally block the progression of T2DM. Therefore, it is imperative to find new ways to prevent and treat diabetes. Traditional Chinese medicine is characterized by multiple components, pathways, and targets with mild and long-lasting effects. Pharmacological studies have shown that nourishing yin traditional Chinese medicine (NYTCM) can play a positive role in the treatment of T2DM by regulating pathways such as the phosphatidylinositol 3-kinase/serine-threonine kinase, mitogen-activated protein kinase, nuclear factor-kappa B, and other pathways to stimulate insulin secretion, protect and repair pancreatic β cells, alleviate insulin resistance, ameliorate disordered glucose and lipid metabolism, mitigate oxidative stress, inhibit inflammatory responses, and regulate the intestinal flora. The pharmacologic activity, mechanisms, safety, and toxicity of NYTCM in the treatment of T2DM are also reviewed in this manuscript.

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Section: Introductionmentioning

confidence: 99%

Nourishing Yin traditional Chinese medicine: potential role in the prevention and treatment of type 2 diabetes

Dai

2024

Am J Transl Res

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“…La diabetes mellitus constituye uno de los problemas sanitarios de mayor trascendencia, tanto por su frecuencia, como por su enorme repercusión socio-económica en el mundo (Alaa et al, 2021). Según la OMS, este problema de salud afecta a 422 millones de personas y causa 1,6 millones de muertes al año.…”

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Factores de riesgo del pie diabético en adulta mayor: caso clínico

Chimborazo

Mesa-Cano

2023

CCD

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Introducción. El pie diabético se define como la infección, ulceración o destrucción de los tejidos profundos del pie que puede estar asociado a diferentes factores. Objetivo. Efectuar un análisis bibliográfico y tratamiento de la enfermedad para determinar los factores de riesgo del pie diabético en adulta mayor mediante un caso clínico del Centro geriátrico FUNPRA de la ciudad de Cañar – Ecuador. Metodología. Paciente de 80 años de edad, sexo femenino, viuda, procedente de la ciudad de Azogues y residente en Cañar-Ecuador FUNPRA (Asilo de ancianos), con ninguna instrucción. Es atendida por pie diabético grado I herida superficial en el pie derecho, no involucra tendón cápsula o hueso, en proceso de cicatrización se observa tejido de granulación. Resultados. Tratamiento y evolución: Se le administró dieta general, actividad física previa curaciones, insulina en la mañana 14 UI/dL y en la tarde 6 UI/dL por día al final curar y vendar. Con 3 años evolución DMT tipo II, 3 meses de evolución de pie diabético. Sin antecedentes patológicos, quirúrgicos y familiares. Se observa mejoría de la paciente después de las curaciones realizadas, control de la glicemia y la administración de la medicación adecuadamente. Conclusión. Se trató a una paciente con diabetes mellitus tipo II, se asocia su pie diabético a la obesidad, al inadecuado cuidado y mala higiene.

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“…The acquired form of DM is type II, as it chiefly results from insulin resistance syndrome [3]. The various fatal adverse effects of type II DM include diabetic foot [4], diabetic bone disease [5], diabetic neuropathy [6], and declined resistance to bacterial and viral infection via affecting the innate immunity [7]. The molecular mechanistic pathway of type II DM is attributed mainly to defects in the kinase molecular signaling pathways, PI3K, p38MAPK, PKA, and calmodulin kinase, which influence glucose metabolism and insulin action [8].…”

Section: Introductionmentioning

confidence: 99%

Therapeutic Screening of Herbal Remedies for the Management of Diabetes

2021

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The study of diabetes mellitus (DM) patterns illustrates increasingly important facts. Most importantly, they include oxidative stress, inflammation, and cellular death. Up to now, there is a shortage of drug therapies for DM, and the discovery and the development of novel therapeutics for this disease are crucial. Medicinal plants are being used more and more as an alternative and natural cure for the disease. Consequently, the objective of this review was to examine the latest results on the effectiveness and protection of natural plants in the management of DM as adjuvant drugs for diabetes and its complex concomitant diseases.

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Diabetic Foot scientific activities in Endocrinology and Metabolism Research Institute

Abstract: Introduction Diabetic Foot (DF) as a common complication of Diabetes should be intensive intervention for prevention, management and rehabilitation. In this regard, Diabetes

Cited by 5 publications

References 22 publications

Nourishing Yin traditional Chinese medicine: potential role in the prevention and treatment of type 2 diabetes

Nourishing Yin traditional Chinese medicine: potential role in the prevention and treatment of type 2 diabetes

Factores de riesgo del pie diabético en adulta mayor: caso clínico

Therapeutic Screening of Herbal Remedies for the Management of Diabetes

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