In this issue of Cancer, investigators from the Taiwan Communitybased Integrated Screening Group report outcomes from an integrated model of multiphasic chronic disease screening in Keelung, Taiwan.1 Their findings represent an important, modern demonstration of a practical and productive approach to preventive health and case finding. The design and outcomes of the Keelung Communitybased Integrated Screening (KCIS) program are noteworthy for several reasons and should reopen the debate not only about the worth, but also the protocol of periodic preventive health examinations.The underlying philosophy of the KCIS program was the potential for the simultaneous ascertainment of two or more asymptomatic chronic conditions, identification of multiple risk factors for metabolic syndrome, enhanced attendance for screening, and more efficient use of resources. Other "linkage" strategies might be equally effective, or be more appropriate for other target audiences. The program focused on five neoplasms (breast, cervical, colorectal, liver, and oral cancers) and three nonneoplastic chronic conditions (diabetes, hypertension, and elevated cholesterol), and education concerning metabolic syndrome. The decision to use the Papanicolaou (Pap) smear registry as a base to build the program was both innovative and practical because screening for cervical cancer is well established and because women can play a pivotal role in monitoring and attending to the health status of other family members. The investigators increased adherence in nonattenders to the Pap smear program by incorporating cervical cancer screening into a broader testing regimen, thus increasing the screening rate in nonattenders who may have been averse to gynecologic screening, with incentives for additional preventive care opportunities for themselves and other family members. Telephone invitations to 30,384 women resulted in 42,387 participants (24,469 women and 17,918 dependents) being seen at 257 health centers. The program increased adherence to cervical cancer screening by 25% (from 55.5% to 80.5%). For all cancer screening, the overall detection of asymptomatic neoplasia was 16 per 1000. Significant numbers of individuals with previously unknown diabetes, metabolic syndrome, hyperlipidemia, and hypertension also were identified. Based on these findings, the investigators estimated that 959 deaths will be averted over a 10-year period after full imple-
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