Diabetes Nutrition and Complications Trial

,

doi:10.2337/diacare.27.4.984

Cited by 43 publications

(10 citation statements)

References 17 publications

(8 reference statements)

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“…In our sample, a relatively low carbohydrate intake (38%), a moderate protein intake (17%) and a high total fat intake, especially due to high intake of monounsaturated fat, are noteworthy. These data are consistent with other Spanish reports and with studies conducted in other countries of the Mediterranean area, in which total caloric intake as well as carbohydrate intake were lower than in non-diabetic subjects, whereas fibre intake was higher [18,19]. …”

Section: Discussionsupporting

confidence: 92%

Adherence to the Mediterranean Diet in Patients with Type 2 Diabetes Mellitus and HbA1c Level

Díez‐Espino¹,

Buil‐Cosiales²,

Serrano-Martínez³

et al. 2011

Ann Nutr Metab

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Rationale and Objective: The Mediterranean diet (MeDiet) has beneficial effects on cardiovascular risk factors. We analyzed the association between adherence of a MeDiet in patients with type 2 diabetes mellitus (T2DM) and levels of HbA1c. Patients and Methods: This was a cross-sectional study in individuals with T2DM participating in the PREDIMED trial at the centre of Pamplona. Information on diet was collected with a validated 14 point scale of adherence to the MeDiet and blood samples were obtained to assess HbA1c levels. Results: We studied 383 participants with T2DM, 53.4% women (mean age 69 ± 6 years). HbA1c data were available in 262 cases (mean 6.9 ± 1.5%). Although there was a potential inverse non-significant association between adherence to MeDiet and HbA1c levels after adjusting for age and sex, it was not statistically significant. Multivariate analysis additionally adjusted for physical activity, smoking, time of evolution of the T2DM, body mass index and insulin treatment found similar findings (OR = 0.69, 95% CI 0.17–2.83). Conclusions: Although we found not enough evidence to support that a MeDiet is associated with lower levels of HbA1c in patients with T2DM, our results suggested an inverse trend. Future studies with larger sample size are necessary.

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Section: Discussionsupporting

confidence: 92%

Adherence to the Mediterranean Diet in Patients with Type 2 Diabetes Mellitus and HbA1c Level

Díez‐Espino¹,

Buil‐Cosiales²,

Serrano-Martínez³

et al. 2011

Ann Nutr Metab

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“…In a study conducted in the year 2000 in four outpatient diabetes clinics [13], less than 10% of diabetic patients consumed <10% of energy in the form of saturated fat and <8% ingested <300 mg/day of cholesterol, versus 37% and 48%, respectively, in the ENRICA study. Moreover, fiber intake was lower than in ENRICA.…”

Section: Discussionmentioning

confidence: 98%

The Diet of Diabetic Patients in Spain in 2008–2010: Accordance with the Main Dietary Recommendations—A Cross-Sectional Study

et al. 2012

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BackgroundNo previous study has assessed the diet of the diabetic patients in the general population of an entire country in Europe. This study evaluates accordance of the diet of diabetic adults in Spain with nutritional recommendations of the European Association for the Study of Diabetes (EASD), American Diabetes Association (ADA), and the Mediterranean diet (MD).Methods and FindingsCross-sectional study conducted in 2008–2010 among 12,948 persons representative of the population aged ≥18 years in Spain. Usual food consumption was assessed with a dietary history. EASD accordance was defined as ≥6 points on a score of 12 nutritional goals, ADA accordance as ≥3 points on a score of 6 goals, and MD accordance as ≥7 points on the Mediterranean Diet Adherence Screener. In the 609 diagnosed diabetic individuals, the diet was rich in saturated fat (11.2% of total energy), but trans fat intake was relatively low (1.1% energy) and monounsaturated fat intake was high (16.1% energy). Carbohydrate intake was relatively low (41.1% energy), but sugar intake was high (16.9% energy). Intake of cholesterol (322 mg/day) and sodium (3.1 g/day) was also high, while fiber intake was insufficient (23.8 g/day). EASD accordance was observed in 48.7% diabetic patients, ADA accordance in 46.3%, and MD accordance in 57.4%. The frequency of EASD, ADA and MD accordance was not statistically different between diagnosed and undiagnosed diabetic individuals.ConclusionsOnly about half of diabetic patients in Spain have a diet that is consistent with the major dietary recommendations. The lack of dietary differences between diagnosed and undiagnosed diabetic individuals reflects deficiencies in diabetes management.

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“…At each follow-up visit, dietary intake and physical activity were evaluated. A semi-quantitative frequency questionnaire, based on the Diabetes Nutrition and Complications Trial (DNCT) study [ 17 ] and the 14-point Mediterranean Diet Adherence Screener (MEDAS) [ 18 ] were used. These were applied to questionnaires to obtain the Nutrition and MEDAS-derived PREDIMED score, respectively.…”

Section: Methodsmentioning

confidence: 99%

A Mediterranean diet with additional extra virgin olive oil and pistachios reduces the incidence of gestational diabetes mellitus (GDM): A randomized controlled trial: The St. Carlos GDM prevention study

et al. 2017

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BackgroundGestational diabetes mellitus (GDM) prevalence is increasing and becoming a major public health concern. Whether a Mediterranean diet can help prevent GDM in unselected pregnant women has yet to be studied.MethodsWe conducted a prospective, randomized controlled trial to evaluate the incidence of GDM with two different dietary models. All consecutive normoglycemic (<92 mg/dL) pregnant women at 8–12 gestational weeks (GW) were assigned to Intervention Group (IG, n = 500): MedDiet supplemented with extra virgin olive oil (EVOO) and pistachios; or Control Group (CG, n = 500): standard diet with limited fat intake. Primary outcome was to assess the effect of the intervention on GDM incidence at 24–28 GW. Gestational weight gain (GWG), pregnancy-induced hypertension, caesarean section (CS), preterm delivery, perineal trauma, small and large for gestational age (SGA and LGA) and admissions to neonatal intensive care unit were also assessed. Analysis was by intention-to-treat.ResultsA total of 874 women completed the study (440/434, CG/IG). According to nutritional questionnaires and biomarker analysis, women in the IG had a good adherence to the intervention. 177/874 women were diagnosed with GDM, 103/440 (23.4%) in CG and 74/434(17.1%) in IG, p = 0.012. The crude relative risk (RR) for GDM was 0.73 (95% CI: 0.56–0.95; p = 0.020) IG vs CG and persisted after adjusted multivariable analysis, 0.75(95% CI: 0.57–0.98; p = 0.039). IG had also significantly reduced rates of insulin-treated GDM, prematurity, GWG at 24–28 and 36–38 GW, emergency CS, perineal trauma, and SGA and LGA newborns (all p<0.05).ConclusionsAn early nutritional intervention with a supplemented MedDiet reduces the incidence of GDM and improves several maternal and neonatal outcomes.

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Diabetes Nutrition and Complications Trial

Cited by 43 publications

References 17 publications

Adherence to the Mediterranean Diet in Patients with Type 2 Diabetes Mellitus and HbA1c Level

Adherence to the Mediterranean Diet in Patients with Type 2 Diabetes Mellitus and HbA1c Level

The Diet of Diabetic Patients in Spain in 2008–2010: Accordance with the Main Dietary Recommendations—A Cross-Sectional Study

A Mediterranean diet with additional extra virgin olive oil and pistachios reduces the incidence of gestational diabetes mellitus (GDM): A randomized controlled trial: The St. Carlos GDM prevention study

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