2020
DOI: 10.31434/rms.v5i9.452
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Diabetes mellitus tipo I

Abstract: La diabetes mellitus tipo 1, se considera una enfermedad altamente prevalente en la población pediátrica, tiene una de etiología autoinmune compleja, que se caracteriza por la destrucción autoinmune de las células beta del páncreas, lo que conlleva a una deficiente producción de insulina, que se manifiesta clínicamente como hiperglicemia. El diagnóstico se realiza en base  al cuadro clínico y hallazgos de  laboratorio. El pilar de tratamiento para alcanzar un control glicémico óptimo es un esquema intensivo co… Show more

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Cited by 2 publications
(3 citation statements)
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“…Autoimmunity: In most cases of DM1, the body's immune system turns against the beta cells of the pancreas. The exact cause of this autoimmune process is unknown, but it is believed that environmental factors such as viral infections may trigger the abnormal immune response (Campos, Ovares y Arens, 2020).…”
Section: Types Of Diabetesmentioning
confidence: 99%
See 1 more Smart Citation
“…Autoimmunity: In most cases of DM1, the body's immune system turns against the beta cells of the pancreas. The exact cause of this autoimmune process is unknown, but it is believed that environmental factors such as viral infections may trigger the abnormal immune response (Campos, Ovares y Arens, 2020).…”
Section: Types Of Diabetesmentioning
confidence: 99%
“…The manifestation of this destruction requires the influence of an environmental trigger, and the rate at which it occurs varies between individuals and may take from a few months (mainly in children) to several years (in adults) before clinical symptoms occur. Approximately 90% of affected individuals show autoimmune markers, such as antibodies against glutamic acid decarboxylase (GAD) and pancreatic islet anti-cytoplasmic antibodies (ICA), among others (Campos, Ovares y Arens, 2020).…”
Section: Types Of Diabetesmentioning
confidence: 99%
“…Según los Centros para el Control y la Prevención de Enfermedades, aproximadamente el 14% de los adultos estadounidenses tienen diabetes, y se estima que otros 84 millones de adultos tienen prediabetes, lo que aumenta el riesgo de desarrollar diabetes tipo 2 en el futuro. (9,10) La diabetes tipo 2 afecta a hombres y mujeres por igual y se presenta con mayor frecuencia en personas mayores de 45 años. También se ha asociado con ciertos factores de riesgo, como la obesidad, la falta de actividad física, la mala alimentación y antecedentes familiares de la enfermedad.…”
Section: Epidemiologíaunclassified