2020
DOI: 10.29184/1980-7813.rcfmc.377.vol.15.n2.2020
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Diabetes Mellitus, Obesidade E Maus Hábitos De Vida: Sua Relação Com a Covid-19

Abstract: No ano de 2019, foi descoberto o vírus que viria a se chamar de SARS-CoV-2 e que provocou uma crise sanitária global. A pandemia de 2020, causada pela doença nomeada de Coronavírus disease 2019 ou COVID-19 alastrou-se rapidamente ao redor do mundo, impactando a população global e, especialmente, alguns grupos de risco, como pacientes com doenças cardiovasculares, obesos e diabéticos, por exemplo. Este estudo possui o objetivo de analisar e relatar as relações existentes entre a COVID-19 e os pacientes que poss… Show more

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“…The association of COVID-19 to cardiopathies generates systemic inflammation due to dysregulation linked to angiotensin-converting enzyme overexpression 2 (ACE2) and elevation of cardiac injury biomarkers [ 47 , 48 ]; in addition, the virus can cause myocardial dysfunction, which aggravates the clinical condition. Among the cases of diabetes, the increase in lethality is due to the difficulty of immune response, mainly innate, due to the hyperglycemic condition, the release of cytokines and the decrease in the release of interferon, responsible for antiviral function [ 49 , 50 ]. On the other hand, cases of obesity have a worsening in the immune response, due to systemic inflammation and consequently, impairment in the performance of defense cells, in addition to coagulation factors, which can lead to the formation of thrombi [ 51 , 52 ].…”
Section: Discussionmentioning
confidence: 99%
“…The association of COVID-19 to cardiopathies generates systemic inflammation due to dysregulation linked to angiotensin-converting enzyme overexpression 2 (ACE2) and elevation of cardiac injury biomarkers [ 47 , 48 ]; in addition, the virus can cause myocardial dysfunction, which aggravates the clinical condition. Among the cases of diabetes, the increase in lethality is due to the difficulty of immune response, mainly innate, due to the hyperglycemic condition, the release of cytokines and the decrease in the release of interferon, responsible for antiviral function [ 49 , 50 ]. On the other hand, cases of obesity have a worsening in the immune response, due to systemic inflammation and consequently, impairment in the performance of defense cells, in addition to coagulation factors, which can lead to the formation of thrombi [ 51 , 52 ].…”
Section: Discussionmentioning
confidence: 99%
“…These conditions may even be present in current cases of acute respiratory syndrome, caused by the SARSCoV-2 virus (Coronavirus 2 of severe acute respiratory syndrome), which causes COVID-19 (Coronavirus Disease 19) 10 , that is a current concern. increasing and already affects 10.5% of the global population, however 44.7% are not diagnosed and, this year, the number of deaths reached 6.7 million people 11 .…”
Section: Introductionmentioning
confidence: 99%