Diabetes mellitus in the era of climate change

Geladari, Eleni; Kounatidis, Dimitris; Geladari, Chara V.; Stratigou, Theodora; Dourakis, Spyridon P.; Andreadis, Emmanuel A.

doi:10.1016/j.diabet.2020.10.003

Cited by 37 publications

(20 citation statements)

References 41 publications

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“…In normal individuals, heat exposure will be dissipated by the body through the skin surface and sweating mechanisms [18]. Both mechanisms were modulated by sympathetic nervous system through hypothalamus respond [20]. This reason underlies the disruption of heat loss from the skin blood flow and sweating in diabetic patients will increase the risk of heat-related illness.…”

Section: The Effect Of Climate Change On T2d Burdenmentioning

confidence: 99%

“…The effect extreme cold exposure on T2D burden. Beside extreme heat exposure, many studies also documented the contribution of extreme cold exposure to the higher risk for morbidity and mortality in diabetes patients [20]. An ecological study between 2006-2013 recruiting more than 1 million T2D patient in Taiwan revealed that low temperature associated with the increasing risk for hypoglycaemic complications and the peak incidence of hypoglycaemia in T2D patients is always found in the January-February period.…”

Section: 12mentioning

confidence: 99%

“…During extreme heat periods, there needs an interventions to ensure that vulnerable T2D patients stay indoors and have access to cooling systems safely. For reducing the risk of patient morbidity during this heat periods, doctors should also identify T2D patients who have susceptibilities such as those with cardiovascular disease, or chronic kidney disease [20].…”

Section: 31mentioning

confidence: 99%

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The bidirectional interaction between climate change and type 2 diabetes burden

Yudhani

Sholikhah

Nugrahaningsih

et al. 2022

IOP Conf. Ser.: Earth Environ. Sci.

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Nowadays, type 2 diabetes (T2D) and climate change are the most urgent issues that being the focus worldwide. Interestingly, T2D directly or indirectly affects climate change and vice versa, climate change also contributes to the increased risk and the mortality of various non-communicable diseases (NCD), including T2D. This review aims to synthesis and give the comprehensive understanding related to interaction between climate change and T2D burden, which still being a limited subject in the Indonesian healthcare sector. It also explores those mechanisms for considering the right strategies and policies addressing those issues, especially the proper strategies for the prevention and management of diabetes. This review was conducted by screening from Google Scholar, Science Direct and PubMed with keywords “diabetes AND climate change”, “diabetes AND extreme temperature”, “diabetes AND cold weather”. Various predisposing factors for the rapid growth of diabetes prevalence (urbanization, physical inactivity, unhealthy diets, and obesity) are also act as a risk vector that triggering climate change. While extreme temperature increases the susceptibility of the diabetic subjects to get life-threatening complications like dehydration and heatstroke. There is bidirectional interaction between climate change and T2D burden, which should be a priority for the government’s attention to achieve the Sustainable Developmental Goal (SDG), especially for NCD including type 2 diabetes.

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Section: The Effect Of Climate Change On T2d Burdenmentioning

confidence: 99%

Section: 12mentioning

confidence: 99%

Section: 31mentioning

confidence: 99%

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The bidirectional interaction between climate change and type 2 diabetes burden

Yudhani

Sholikhah

Nugrahaningsih

et al. 2022

IOP Conf. Ser.: Earth Environ. Sci.

View full text Add to dashboard Cite

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“…The biological mechanisms of the effects of extreme temperatures on diabetes are not fully understood as yet. Potential biological mechanisms include, but are not limited to, neurological pathways, hemodynamic effects (Ely et al 2018;Kenny et al 2016;Vallianou et al 2020), brown adipose tissue (Symonds et al 2019). During heat and cold exposure, cardiovascular regulation is essential for temperature control, so blood must be redistributed to the periphery and to the core respectively to maintain a stable core temperature and thus maintain the body's thermal balance (Kenny et al 2016).…”

Section: Potential Biological Mechanismsmentioning

confidence: 99%

Impact of short-term exposure to extreme temperatures on diabetes mellitus morbidity and mortality? A systematic review and meta-analysis

Song

Jiang

Zhang

et al. 2021

Environ Sci Pollut Res

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The relationship between diabetes mellitus and short-term exposure to extreme temperatures remains controversial. A systematic review and metaanalysis were performed to assess the association between extreme temperatures and diabetes mellitus morbidity and mortality. PubMed, Embase, the Cochrane Library, Web of Science and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) were searched since inception to January 1, 2019, and updated on November 17, 2020. The results were combined using random effects model and reported as relative risk (RR) with 95% con dence interval (CI). 32 studies met the included criteria. (1) Both heat and cold exposures have impact on diabetes. (2) For heat exposure, the subgroup analysis revealed that the effect on diabetes mortality (RR = 1.139, 95% CI: 1.089-1.192) was higher than morbidity (RR = 1.012, 95% CI: 1.004-1.019). (3) With the increase of de nition threshold, the impact of heat exposure on diabetes rised. (4) A stronger association between heat exposure and diabetes was observed in the elderly (≥ 60 years old) (RR = 1.040, 95% CI: 1.017-1.064). In conclusion, both short-term exposure to heat and cold temperatures have impact on diabetes. The elderly is the vulnerable population of diabetes exposure to heat temperature. Developing de nitions of heatwaves at the regional level are suggested.

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“…Type 2 diabetes mellitus (T2DM) is a growing health problem worldwide, largely because of the high burden of increasing obesity rates [ [1] , [2] , [3] ]. In comparison with intensive medical therapy, Roux-en-Y gastric bypass (RYGB) surgery is a particularly effective intervention for T2DM, with about 60% of obese individuals achieving T2DM remission (DR) and sustained weight loss [ 4 , 5 ].…”

mentioning

confidence: 99%