Diabetes mellitus in pregnancy in an African population

Ozumba, Benjamin C.; Obi, SN; Oli, Johnnie

doi:10.1016/s0020-7292(03)00210-8

Cited by 47 publications

(52 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The established incidence of 5.1% for DM in pregnancy in the current study is much higher than previously reported rates of 1.7% [17] and 3% [7] . However, the incidence of pregestational DM in the study (0.8%) is comparable with the 1% incidence reported for the USA [12] , while the incidence of the GDM in our study, 4.3%, is within the range of 1-14% reported for the USA [3] .…”

Section: Discussioncontrasting

confidence: 78%

Intrapartum Performance of Patients Presenting with Diabetes Mellitus in Pregnancy

Diejomaoh

Gupta²,

R³

et al. 2009

Med Princ Pract

View full text Add to dashboard Cite

Objective: To investigate the intrapartum performance of pregnancies complicated by diabetes mellitus (DM). Subjects and Methods: A pilot study (April–June 2005) of medical records of patients with DM admitted into the labour wards of the Maternity Hospital, Kuwait, was undertaken. Consecutive patients, matched for age and parity with the study group and with no medical complications, admitted for induction of labour during the study period served as the control. The ethnicity, obstetric/medical history and antenatal course of the index pregnancy were extracted. The intrapartum, postpartum and the neonatal outcome were documented. Statistical analysis was performed using χ² and alternative Welch t tests. Results: During the study period, 3,005 patients were delivered at the hospital, and 177 of these (the study population) presented with DM, an incidence of 5.9%. Another 177 patients admitted for induction of labour served as the control. Of the 177 study patients, 86 (48.6%) were Kuwaitis, and the remaining 91 (51.4%) were non-Kuwaitis, of whom 41 were Arabs (23.2%), 34 Indians (19.2%), and 16 Asians (9%). Of the controls, 65 (36.7%) and 112 (63.3%) were Kuwaitis and non-Kuwaitis, respectively. Of the 177 study patients, 128 (72.3%) presented with gestational DM. The significant complications were pregnancy-induced hypertension (13, 7.3%) and premature rupture of membranes (14, 7.9%). The incidence of caesarean section in the study population (58, 32.8%) was significantly higher than that of the controls (35, 19.8%; p = 0.008). Although the mean gestational ages at delivery in both groups were comparable (p = 0.669), the mean birth weight in the study group was significantly higher, 3.315 ± 0.605 vs. 3.160 ± 0.594 kg (p = 0.012). The neonatal complications in the diabetic patients were shoulder dystocia (4, 2.3%) and Erb’s palsy (12, 1.1%); there were more perinatal deaths (3) in the control group. Conclusion: The incidence of DM was high, and the rate of caesarean section significant. The maternal and neonatal morbidity were high. A prospective study is recommended for enhanced management guidelines.

show abstract

Section: Discussioncontrasting

confidence: 78%

Intrapartum Performance of Patients Presenting with Diabetes Mellitus in Pregnancy

Diejomaoh

Gupta²,

R³

et al. 2009

Med Princ Pract

View full text Add to dashboard Cite

show abstract

“…2,24 In a different population, the reported prevalence was approximately 1%. 25 In this retrospective study of antenatal patient population who were selectively screened for GDM, FBS test method identified as much as 9% prevalence, excluding another 8% that could be termed gestational prediabetes. Indeed, it is estimated that prevalence of GDM ranges from 1 to 14%, or average of 7%, depending on method of testing and population.…”

Section: Discussionmentioning

confidence: 95%

Screening for gestational diabetes: evaluation of prevalence in age-stratified subgroups at Central hospital Warri Nigeria

Orru

Nwose

Bwititi³

et al. 2017

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: The prevalence of gestational diabetes depends on the method of diagnosis as well as ethnic background. Maternal age has also been identified as a factor, but has not been given much attention. The notion of gestational prediabetes has also speculated, but is equally yet to be a focus in discussion. Aim: This work aimed at evaluating the screening for gestational diabetes in Central Hospital, Warri; to determine prevalence of gestational diabetes in the general population and in stratified age groups. The other objective was to investigate the effectiveness and use of the methods of diagnosis. Materials and Methods: This was a retrospective review of laboratory data of de-identified antenatal patients. Hospital records of gestational diabetes from 2013 to 2015 were obtained from the Central Hospital, Warri. Data collected included age of the de-identified patients, blood glucose results and whether the test was fasting or random. Other information was the month/year of test. A total of 3 589 results were analyzed. Results: Averaged prevalence of 5.85% is identified. Fasting blood sugar (FBS) measurement was used more and it also identified more positives (9%) compared to random blood sugar (<2%). On a dichotomous age group, prevalence of gestational diabetes appeared low in women below 25 years compared to those ≥26 years old. In a more stratification of age groups, potential antepartum prediabetes in pregnancy was lower in women above 40 years old relative to the younger age subpopulations (p < 0.000001). No significant variation was observed in level of usage of either method between months/years. Conclusion: There is an ongoing good practice of using affordable screening test, which is FBS. The significant finding was that there may be up to 9% prevalence of GDM and that this number may erroneously be lower if random blood glucose measurement is used. Another worthy observation was that the prevalence in stratified age groups was non-directional, especially as prediabetes appears higher in the younger age subpopulation.

show abstract

“…Delivery by CS was more common in Group A (83.3%) than Group B (61.9%). According to Ozumba et al the overall cesarean section rate was high (36%) among diabetics with previous cesarean section and cephalopelvic disproportion being the commonest indications 30 . There is also increased risk of macrosomia in male infants as compared to female ones.…”

Section: Discussionmentioning

confidence: 99%

Neonatal Outcomes of Large-for-Gestational Age Infants with or without Gestational Diabetes Mellitus

Begum

Chowdhury

et al. 2018

Chatt Maa Shi Hosp Med Coll J

View full text Add to dashboard Cite

Background: Infants are considered Large for Gestational Age (LGA)if their birth weight is greater than the 90th percentile for gestational age. Birth weight is influenced by a number of factors with maternal diabetes being one of the most common risk factor affecting birth weight. They have an increased risk for adverse perinatal outcomes. The aim of the present study was to compare the neonatal outcomes of LGA infants delivered by women with and without gestational diabetes mellitus. Methods: This is a prospective study of all live-born LGA infants of 37 weeks of gestation with a birth weight of 4000g admitted at Neonatal ward of Chattagram Maa Shishu-O-General Hospital (CMSOGH) between 1 st August 2013 to 31 st July 2014. Type of sampling was purposive convenient sampling. A total of 51 neonatal patients were included. Data was collected in case record form. Data collected for the mothers included age, parity, gestational age and mode of delivery. Data for the infants include sex, birth weight, birth length and laboratory test. Outcomes were compared between infants of diabetic mothers (Group A) and infants of non-diabetic mothers (Group B). Then data was analyzed by SPSS 17.0 program and presented by tabular method, diagram and chart. Results: Among fifty one study subjects, thirty were Infants of Diabetic Mothers (IDMs) while twenty one were nonIDMs. 19 (63.3%) of the IDMs were male while 11 (36.7%) were female. Among the 21 non-IDMs 10 (47.6%) were male and 11 (52.4%) were female. Male to female ratio was 1.4:1. 5 (16.7%) of the IDMs were delivered vaginally while 25 (83.3%) were delivered by Caesarian Section (CS) where as 8 (38.1%) of the nonIDMs were delivered vaginally while 13 (61.9%) were delivered by CS. Respiratory distress was the most common morbidity affecting 70% of the IDMs and 66.7% of the non-IDMs. TTN accounted for the majority of the respiratory distress cases, occurring in 17 of the IDMs and 12 of the non-IDMs. Regarding analysis of other clinical features, convulsion (63.3%) was present more in IDMs than in non-IDMs (52.4%) cyanosis was found more in IDMs (60%) than non-IDMs (38.1%). Hypoglycemia was found more in IDMs than in non-IDMs. Mean glucose values were 41.06±19.91mg/dl for IDMs and 53.06±28.96mg/dl for the non-IDMs (p=0.001). Hyperbilirubinemia was more frequently observed in IDMs than in nonIDMs. About 17 (56.6%) of the IDMs and 7(33.3%) of the non-IDMs developed jaundice during the period of hospital stay. Polycythemia was not observed in both the groups but PCV was higher in IDMs (53.96±6.36) compared to non-IDMs (50.50±8.76). Hypocalcemia was not peculiar to a specific group. Five of the IDMs had congenital anomaly, of which three of them had cardiac anomaly. One of the non-IDM was suffering from ventricular septal defect. Birth asphyxia was observed more in non-IDMs (71.4%) than in IDMs (53.3%).One of the IDMs and two of the non-IDMs sustained a brachial plexus injury following vaginal delivery.

show abstract

Diabetes mellitus in pregnancy in an African population

Abstract: Health education and provision of modern affordable methods of management of diagnosed cases such as uristix and hemastix will improve maternal and fetal outcome in pregnant diabetics in Africa.

Cited by 47 publications

References 9 publications

Intrapartum Performance of Patients Presenting with Diabetes Mellitus in Pregnancy

Intrapartum Performance of Patients Presenting with Diabetes Mellitus in Pregnancy

Screening for gestational diabetes: evaluation of prevalence in age-stratified subgroups at Central hospital Warri Nigeria

Neonatal Outcomes of Large-for-Gestational Age Infants with or without Gestational Diabetes Mellitus

Contact Info

Product

Resources

About