Diabetes mellitus and pyoinflammatory diseases of ENT organs

Biryukova, E. V.; Валерьевна, Бирюкова Елена; Гуров, А. В.; Владимирович, Гуров Александр; Yushkina, M. A.; Алексеевна, Юшкина Марина

doi:10.14341/2072-0351-5519

Cited by 8 publications

(3 citation statements)

References 8 publications

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“…шения (сахарный диабет), различные гиповитаминозы, аллергические и кожные заболевания (экзема, псориаз, атопический дерматит), вторичные иммунодефицитные состояния [4,5]. Все это приводит к инфицированию и (или) активизации сапрофитной флоры НСП и развитию воспалительного процесса.…”

Section: Abstract: Diffuse External Otitis Inflammation Of the Exterunclassified

The current views of the treatment of diffuse external otitis

2016

Vestn. otorinolaringol.

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The objective of the present study was to evaluate the clinical effectiveness and safety of the local application of triderm for the treatment of diffuse external otitis. The study included 68 patients presenting with bacterial and fungal diffuse external otitis. The treatment in the form of local empiric therapy was continued till the results of microbiological treatment became apparent. The beneficial outcome achieved in 91.2% of the patients was clinically manifest as the regression of the inflammatory process in the external auditory meatus. No complications, such as ototoxic events, either local or systemic allergic reactions, were documented. The authors substantiate the possibility of the application of the medication under consideration for the treatment of diffuse external otitis based on the knowledge of the mechanism of the actin of its constituent components, viz. betamethasone, dipropionate, gentamicin sulfate, and clotrimazole, taking into account the occurrence of the most common causative agents of diffuse external otitis. It is concluded that triderm is a safe medication for the local application and, probably, for the initial empiric therapy of diffuse external otitis to be continued till the results of the microbiological treatment become apparent.

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Section: Abstract: Diffuse External Otitis Inflammation Of the Exterunclassified

The current views of the treatment of diffuse external otitis

2016

Vestn. otorinolaringol.

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“…Clinical and pathogenetic features of ENT diseases, in particular otiatric pathology, in conditions of comorbidity with diabetes mellitus are being actively studied [16,17]. Variants of the clinical course of inflammatory diseases of soft tissues (furuncle, phlegmon of the neck), pharynx (tonsillitis, paratonsillar and parapharyngeal obscesses) [18,19], paranasal sinuses [20], features of sensorineural hearing loss in otolaryngological patients on the background of non-insulin-dependent diabetes mellitus (DM type II) are described [17]. The pathogenetic significance of non-insulin dependent diabetes mellitus for the formation of a special form of otitis externa, the socalled malignant otitis externa, has been shown in numerous publications [21,22].…”

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Features of the clinical course of acute otitis media in patients with impaired carbohydrate metabolism

Pochuiеva

Filatova

2022

Eureka: HS

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The aim of the research: study of the features of the clinical course of acute otitis media (AOM) in patients with impaired carbohydrate metabolism. Materials and methods. We examined 140 patients with AOM aged 19 to 72 years, of which 75 patients with impaired carbohydrate metabolism constituted the main group and 65 patients were included in the comparison group. Taking into account the peculiarities of the pathogenesis of AOM and disorders of carbohydrate metabolism, patients were randomized into 4 groups: 1 – patients with AOM (36), 2 – patients with AOM on the background of sinusitis (29), 3 – patients with AOM on the background of non-insulin-dependent diabetes mellitus (DM type II) (37), 4 – AOM patients with impaired glucose metabolism (38). The patients underwent a general clinical examination, determination of glycosylated hemoglobin, leukocyte indices of intoxication, audiometry, computed tomography (CT) of the temporal bones (if indicated). Results. The proportion of patients with impaired carbohydrate metabolism in 2020 was 32.6 %, of which DM type II was diagnosed in 49.3 % earlier. It was shown that a feature of the clinical course of AOM against the background of impaired carbohydrate metabolism is the discrepancy between the duration of the disease history, complaints and objective data to the state of the cellular structure of the mastoid process according to CT data and impaired auditory function mainly by the type of sound perception, which indicates the formation of latent mastoiditis. Clinically significant complaints and objective data for the differential diagnosis of latent mastoiditis in these patients were determined. The absence of statistical significance of differences in indicators in patients with DM type II and against the background of transient hyperglycemia was revealed, and the concept of the latter was characterized. A direct correlation between blood glucose levels and glycated hemoglobin levels was established in patients with DM type II and AOM. Conclusions. DM type II creates a favorable background for the formation of the clinical course of AOM complicated by latent mastoiditis. From the general contingent of patients with AOM, patients should be distinguished not only with DM type II, but also with transient hyperglycemia for its timely diagnosis. Significant symptoms: pain and a feeling of “heaviness” in the behind-the-ear region in the absence of reactive phenomena, a feeling of “pulsation” in the ear, dizziness, a cloudy eardrum with a protrusion or perforation in the posterior or posterior-upper section, an asymmetric increase in sound perception thresholds above 25 dB. Such patients should be observed with “early” CT scan of the temporal bones.

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“…При этом наблюдается повышение гликемического профиля, усиливаются гипергликемия и глюкозурия [19]. В свою очередь декомпенсация углеводного обмена негативно сказывается на течении инфекции небных миндалин [20,21].…”

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Tonsillitis and tonsillogenic conditions

Karpishchenko

Lavrenova

Baranskaya

2016

Vestn. otorinolaringol.

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The objective of the present study was to analyze and summarize the literature publications concerning tonsillitis and related (tonsillogenic) pathological conditions. The retrospective analysis of these materials made it possible to collect and summarize information about the influence of palatine tonsillar pathology (chronic tonsillitis) on the function of various organs and their systems. It has been shown that pathogenesis of a great variety of disease is underlain by pathology of palatine tonsils. Also, the possibility to stabilize the pathological processes in certain organs and systems by the conservative and/or surgical treatment of chronic tonsillitis has been demonstrated. It is concluded that the patients presenting with chronic tonsillitis make up a group of risk of development of many serious somatic diseases and require enhanced attention not only of otorhinolaryngologists but also specialists representing other medical disciplines. The multidisciplinary approach to the management of such patients is the sole way to reduce the frequency ofgeneral complications in the patients with chronic tonsillitis.

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Diabetes mellitus and pyoinflammatory diseases of ENT organs

Abstract: Current review addresses diagnostic issues and treatment of patients with diabetes mellitus (DM) and pyoinflammatory diseases ofENT organs. We discuss etiologic and pathogenetic factors affecting course of pyoinflammatory processes in ENT organs of diabeticpatients

Cited by 8 publications

References 8 publications

The current views of the treatment of diffuse external otitis

The current views of the treatment of diffuse external otitis

Features of the clinical course of acute otitis media in patients with impaired carbohydrate metabolism

Tonsillitis and tonsillogenic conditions

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