Diabetes mellitus and acquired haemophilia: new association?

Abstract

Diabetes mellitus encompasses a group of highly prevalent carbohydrate metabolic disorders with an increasing incidence. Some subtypes are thought to be associated with other immune-mediated diseases. Acquired haemophilia on the other hand is a quite rare autoimmune disease that is thought to be secondary to the emergence of inhibiting anticoagulation factor VIII antibodies (inhibitors) in patients with previously normal haemostatic function. More recently, numerous different diseases have been associated with acquired haemophilia namely immune-mediated diseases, drugs and solid and haematologic neoplasms. The authors report on a case of a patient with new onset acquired haemophilia arising in the setting of diabetic ketoacidosis.

Correspondence on COVID-19 Vaccination and Acquired Haemophila A

“…There has been a link between these two disorders and AHA. 2,3 The present patient was given rituximab and steroid. Six weeks following diagnosis, his Factor VIII level was normal and his inhibitor screen was negative.…”