Diabetes mellitus adversely affects mortality and recurrence after valve surgery for infective endocarditis

Yoshioka, Daisuke; Toda, Köichi; Yokoyama, Junya; Matsuura, Ryohei; Miyagawa, Shigeru; Kainuma, Satoshi; Sakaguchi, Taichi; Sakaki, Masayuki; Nishi, Hiroyuki; Shirakawa, Yukitoshi; Iwata, Keiji; Suhara, Hitoshi; Sakaniwa, Ryoto; Fukuda, Hirotsugu; Sawa, Yoshiki

doi:10.1016/j.jtcvs.2017.09.013

Cited by 22 publications

(15 citation statements)

References 26 publications

(39 reference statements)

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“…Notably, the prevalence of diabetes was significantly higher in the EIE group, which is inline with previous findings on diabetes predicting poorer outcomes in this patients population. 5,6 The authors also demonstrated left ventricular ejection fraction and estimated glomerular filtration rate to be statistically significant predictive factors for poor outcomes in such patients, which is also consistent with prior investigations. 7 Second, Huuskonen et al identified the female gender to be a protective factor for overall mortality.…”

supporting

confidence: 84%

Outcomes for extensive infective endocarditis: One, no one, and one hundred thousand

Amabile

Weininger

Geirsson

2021

Journal of Cardiac Surgery

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supporting

confidence: 84%

Outcomes for extensive infective endocarditis: One, no one, and one hundred thousand

Amabile

Weininger

Geirsson

2021

Journal of Cardiac Surgery

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“…Some studies have also confirmed that these factors were associated with in hospital mortality [8,[22][23][24][25][26]. And perivascular abscess [19], diabetes mellitus [27,28], or acute renal failure [26,29] have also been reported to be the risk factors of high mortality. Interestingly, medical therapy was associated with higher in-hospital mortality, which suggested the protective role of surgical treatment.…”

Section: Discussionmentioning

confidence: 90%

Infective endocarditis at a tertiary-care hospital in China

et al. 2020

J Cardiothorac Surg

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Background: The aim of this study was to describe the clinical features and outcome of infective endocarditis at a general hospital in China and to identify the risk factors associated with in-hospital mortality. Methods: A retrospective study was conducted and all patients diagnosed with definite or possible infective endocarditis between January 2013 and June 2018 according to the modified Duke criteria were included. Results: A total of 381 patients were included. The mean age was 46 years old and 66.9% patients were male patients. Community acquired IE was the most common type of infective endocarditis and Viridans Group Streptococci (37.5%) was still the most common causative pathogen. The microbial etiology of infective endocarditis varied with location of acquisition. 97 (25.5%) patients had culture-negative infective endocarditis. Vegetations were detected in 85% patients and mitral valve was the most common involved valve. Operations were performed in 72.7% patients and in-hospital mortality rate was 8.4%. The risk factors of in-hospital mortality were age old than 70 years old, heart failure, stroke and medical therapy. Conclusions: Older age, heart failure, stroke and medical therapy were risk factors of in-hospital mortality. Infective endocarditis, were mainly caused by Viridans Group Streptococci, characterized by younger patients and lower mortality rate in China.

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“…However, highest mortalities occur with S. aureus and the non-HACEK group pathogens such as Candida albicans (Ashrafi et al, 2012). Additionally, infective endocarditis also can occur in intravenous drug abusers or in association with HIV infection, diabetes mellitus, rheumatoid arthritis, Sjögrens syndrome and cancer (Miro et al, 2002;Filizcan et al, 2004;Sughimoto et al, 2006;Yoshioka et al, 2018;Sanaiha et al, 2019; Table 1). These observations suggest that multiple pathomechanisms may contribute to the development of endocarditis.…”

Section: Endocarditismentioning

confidence: 99%

Triggers of Inflammatory Heart Disease

Lasrado

Yalaka

Reddy

2020

Front. Cell Dev. Biol.

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Inflammatory heart disease (IHD) is a group of diseases that includes pericarditis, myocarditis, and endocarditis. Although males appear to be more commonly affected than females, IHD can be seen in any age group. While the disease can be self-limiting leading to full recovery, affected individuals can develop chronic disease, suggesting that identification of primary triggers is critical for successful therapies. Adding to this complexity, however, is the fact that IHD can be triggered by a variety of infectious and non-infectious causes that can also occur as secondary events to primary insults. In this review, we discuss the immunological insights into the development of IHD as well as a mechanistic understanding of the disease process in animal models.

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Diabetes mellitus adversely affects mortality and recurrence after valve surgery for infective endocarditis

Abstract: The short- and mid-term outcome after valve surgery for active IE in patients with DM is worse because of the greater prevalence of infection-related death and IE recurrence.

Cited by 22 publications

References 26 publications

Outcomes for extensive infective endocarditis: One, no one, and one hundred thousand

Outcomes for extensive infective endocarditis: One, no one, and one hundred thousand

Infective endocarditis at a tertiary-care hospital in China

Triggers of Inflammatory Heart Disease

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