Diabetes Mechanisms, Detection and Complications Monitoring

Ghista, Dhanjoo N.; Acharya, U. Rajendra; Desai, Kamlakar D.; Dittakavi, Sarma S.; Adeneye, Adejuwon Adewale; Meng, Loh Kah

doi:10.5772/38870

Cited by 1 publication

(2 citation statements)

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“…The term diabetes, which was first used by the Greek doctor Aretus in the 2nd century, was defined by the WHO in 1999 as a metabolic disorder resulting in disruptions in carbohydrate, fat, and protein metabolism due to insulin secretion or the effects of insulin [ 65 ]. Diabetes mellitus (DM) is a metabolic disease that was briefly defined as high blood sugar for a long time.…”

Section: Introductionmentioning

confidence: 99%

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Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections

Ekiz

Öz

El‐Aty

et al. 2023

Foods

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Ganoderma lucidum is a medicinal mushroom that has been traditionally used in Chinese medicine for centuries. It has been found to have a wide range of medicinal properties, including antioxidant, anti-inflammatory, and immune-boosting effects. Recent research has focused on the potential benefits of G. lucidum in treating metabolic disorders such as diabetes and obesity, as well as its possible role in preventing and treating infections caused by the coronavirus. Triterpenoids are a major group of bioactive compounds found in G. lucidum, and they have a range of biological activities, including anti-inflammatory and antioxidant properties. These compounds have been found to improve insulin sensitivity and lower blood sugar levels in animal models of diabetes. Additionally, G. lucidum polysaccharides have been found to reduce bodyweight and improve glucose metabolism in animal models of obesity. These polysaccharides can also help to increase the activity of certain white blood cells, which play a critical role in the body’s immune response. For coronavirus, some in vitro studies have shown that G. lucidum polysaccharides and triterpenoids have the potential to inhibit coronavirus infection; however, these results have not been validated through clinical trials. Therefore, it would be premature to draw any definitive conclusions about the effectiveness of G. lucidum in preventing or treating coronavirus infections in humans.

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Section: Introductionmentioning

confidence: 99%

“…Diabetes progresses when normal fasting blood sugar, which is in the range of 70–100 mg/dL, is constantly above these values. This change in blood sugar is due to insulin deficiency or obstructive factors in the tissues that incorporate insulin into metabolism [ 65 ]. Diabetes is seen in two main forms: Type 1 and Type 2.…”

Section: Introductionmentioning

confidence: 99%