Diabetes and the Skin

Gisondi, Paolo; Fostini, A. C.; Girolomoni, Giampiero

doi:10.1007/978-3-319-44433-8_14

Cited by 2 publications

(4 citation statements)

References 41 publications

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“…It is characterized by recurrent non-inflammatory, painful blisters with spontaneous onset and self-limiting course. 1,2 It occurs in 0.5 to 2% of diabetics, with a predilection for male patients and greater recurrence in lower limbs, particularly the feet. Although rarer, it can also affect the upper limbs, hands, and fingers.…”

Section: Introductionmentioning

confidence: 99%

“…Although rarer, it can also affect the upper limbs, hands, and fingers. 1,3 We report the case of a patient with ulcers of the upper limbs diagnosed with bullosis diabeticorum. Since this condition is uncommon in this location, with few cases reported in the literature, the objective of this article is to highlight the importance of knowledge of the possible differential diagnoses of cutaneous lesions in diabetic patients.…”

Section: Introductionmentioning

confidence: 99%

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Bullosis diabeticorum as a differential diagnosis for limb ulcers: case report

et al. 2022

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Bullosis diabeticorum (BD) is an uncommon cutaneous manifestation of diabetes that can affect the upper limbs. It is characterized by spontaneous and painless non-inflammatory bloody blisters, which can progress to necrosis, requiring differential diagnosis to rule out other dermatological diseases, such as porphyria cutanea tarda, pseudoporphyria, epidermolysis bullosa acquisita, and pemphigoid, and vascular diseases, such as vasculitis, peripheral arterial disease, and Buerger’s disease, among others. In this report, we describe a 77-year-old male patient with poorly controlled diabetes and hypertension who presented with spontaneous onset of lesions on the upper limbs, initially with bullous characteristics, progressing to necrotic ulcers after spontaneous rupture. A biopsy revealed hyaline thickening of the dermal vessels and subcorneal bullae, consistent with a diagnosis of BD. After smoking cessation and optimization of glycemia control combined with topical corticosteroid therapy, the condition improved and lesions began to heal. This presentation of BD involving the upper limbs is rare, requiring differential diagnosis to rule out other cutaneous and vascular lesions.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Bullosis diabeticorum as a differential diagnosis for limb ulcers: case report

et al. 2022

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“…A bullosis diabeticorum é uma manifestação cutânea infrequente do diabetes. Caracteriza-se por bolhas não inflamatórias, indolores, de aparecimento espontâneo e de curso autolimitado e recorrente 1 , 2 . Ela ocorre em 0,5 a 2% dos diabéticos, com maior acometimento em pacientes do sexo masculino, sendo mais recorrente nos membros inferiores, sobretudo nos pés.…”

Section: Introductionunclassified

“…Ela ocorre em 0,5 a 2% dos diabéticos, com maior acometimento em pacientes do sexo masculino, sendo mais recorrente nos membros inferiores, sobretudo nos pés. Apesar de mais raramente, também pode afetar os membros superiores, mãos e quirodáctilos 1 , 3 .…”

Section: Introductionunclassified

Bullosis diabeticorum como diagnóstico diferencial de úlcera de membros: relato de caso

et al. 2022

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Resumo A bullosis diabeticorum (BD) é uma manifestação cutânea infrequente do diabetes e pode afetar os membros superiores. Caracteriza-se pelo aparecimento espontâneo e indolor de flictenas não inflamatórias de aspecto sanguinolento, que podem evoluir para necrose, requerendo que se faça diagnóstico diferencial com doenças dermatológicas, como porfiria cutânea tarda, pseudoporfiria, epidermólise bolhosa adquirida e penfigoide bolhoso, e doenças vasculares, como vasculites, doença arterial periférica, doença de Buerger, entre outras. Neste relato, descreve-se o caso de um paciente masculino de 77 anos, hipertenso e diabético mal controlado, apresentando aparecimento espontâneo de lesões bolhosas de membros superiores, que evoluíram, após ruptura espontânea, para ulcerosas necróticas. A biópsia da lesão diagnosticou a presença de espessamento hialino de vasos dérmicos e de bolhas subcórneas, compatíveis com o diagnóstico de BD. Após a interrupção do tabagismo e a otimização do controle glicêmico associado a corticoterapia tópica, houve melhora, com cicatrização das lesões. A apresentação da BD em membros superiores é mais rara, sendo necessário o diagnóstico diferencial com outras lesões cutâneas e vasculares.

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Diabetes and the Skin

Cited by 2 publications

References 41 publications

Bullosis diabeticorum as a differential diagnosis for limb ulcers: case report

Bullosis diabeticorum as a differential diagnosis for limb ulcers: case report

Bullosis diabeticorum como diagnóstico diferencial de úlcera de membros: relato de caso

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