Diabetes and Periodontal Disease: An Update for Health Care Providers

Persson, G. Rutger

doi:10.2337/diaspect.24.4.195

Cited by 23 publications

(6 citation statements)

References 32 publications

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“…People with poorly controlled diabetes (who are also at great risk of other macrovascular and microvascular complications) are at increased risk of periodontitis and loss of alveolar bone (41,42). Given the expected rises in the prevalence of diabetes over the next few decades, the previously observed declines in the majority of Periodontitis (associated with less smoking and improved oral health behavior in recent years) are likely to be reversed as a consequence of a significant rise in the number of people with diabetes (43). It is possible that diabetes management (i.e., improving glycaemic control) would decrease the risk and severity of Periodontitis.…”

Section: Resultsmentioning

confidence: 99%

Diagnosis and detection of VicK gene in Streptococcus mutans isolated from the saliva of patients with diabetic type 2 with tooth decay in the Iraqi population

Al-Sudani¹,

Hamad

Ali

2022

Cell Mol Biol (Noisy-le-grand)

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Type 2 diabetes mellitus (T2DM) is gradually becoming more common in Iraq. Salivary changes and proliferation of specific bacterial communities cause oral disease that can adversely affect systemic conditions such as diabetes. Fifty saliva samples were collected from people with T2DM suffering from tooth decay and twenty-five people without T2DM suffering from tooth decay. The periodontal status, the extent of the root surface, and coronal caries were evaluated. Saliva was cultured for investigating Streptococcus mutans. The results showed that patients with type 2 diabetes had significantly more severe Periodontitis and a higher prevalence and magnitude of bacterial caries. Diabetic subjects had higher levels of Hemoglobin A1c (HbA1c) and Random Blood Sugar (R.B.S.). The S. mutans diagnosis by PCR for Sanger Sequencing technique by using VicK gene sequences (1300bp). The PCR products of the isolate were submitted to Macrogen Company for sequencing. Selected seven isolates as new isolates registered in global gene bank as locally S. Mutans isolates in Bagdad city/Iraq and their accepted accession numbers include LOCUS MT603520, MT603521, MT603522, MT603523, MT603524, MT603525,and MT603526 of nucleotide sequence. The VicK genes isolates' phylogenetic trees revealed a genotype that was closely connected to other isolates in GenBank. Furthermore, gene sequencing demonstrated a success rate of 99 percent. resemblance to other isolates in the GenBank database The likelihood of a link between S. Mutans and dental carries was determined by these findings.

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Section: Resultsmentioning

confidence: 99%

Diagnosis and detection of VicK gene in Streptococcus mutans isolated from the saliva of patients with diabetic type 2 with tooth decay in the Iraqi population

Al-Sudani¹,

Hamad

Ali

2022

Cell Mol Biol (Noisy-le-grand)

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“…The current research also supports that the patients having uncontrolled diabetes type-2 have severe and more bone loss as compare to the patients having diabetes type-2 but controlled levels of glucose in the blood. In 2011, Persson 19 conducted a survey which stated that if the HbA1c levels increases in blood the bone loss will be severe and more as compared to the controlled blood glucose levels patients. The results of the survey also supported the current study results comparing the HbA1c levels and bone loss in patients, which proves the strong association of HbA1c levels and bone loss.…”

Section: Discussionmentioning

confidence: 99%

Severity of Alveolar Bone Loss in Control and Uncontrolled Type II Diabetics

Farooq¹,

Riasat²,

Baloch³

et al. 2021

PJMHS

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Objective: To assess the association between the controlled and uncontrolled type-2 diabetic patients to the severity of Alveolar bone loss Study Designed: Cross-sectional analytical study. Place and Duration of Study: Department of Radiology, Sardar Begum Dental College and Khyber College of Dentistry Peshawar KPK from 1st October 2020 to 31st March 2021. Methodology: One hundred and seventy patients were included. Daniel formula (1999) was used for the patient to check the alveolar bone loss and questionnaire was filled by the researcher and examination was done on the dental unit using examination instruments. Results: The mean age was 39.41±6.92. The oral hygiene status in patients visiting the radiology department using toothpaste twice a day was 50.58% while bone loss among patient using toothpaste and brushing their teeth twice a day was 21.51%. The patient with a controlled glucose level was 41.28% while a patient with an uncontrolled glucose level was 58.72%. The bone loss in a patient with controlled HbA1c the bone loss in normal to moderate 38.38%while severe bone loss was 2.90% which is less as compared to the controlled group. The bone loss was reported higher in males (51.16%)as in females were 48.84%, but there was a severe bone loss in females 31,40% as compared to males 17.44%. Conclusion: There is a strong association between alveolar bone loss with the increased level of HbA1c. When the levels of HbA1c level increased the bone loss in both male and female was reported high. Type 2 diabetic patients having increased HbA1c levels cause severe bone loss. Keywords: Diabetes mellitus, Out-patient department, Hemoglobin A1c

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“…Since diabetes and periodontitis are both common chronic diseases affecting adults, so it might be beneficial for all dental offices to monitor the blood glucose levels of patients considered to be at risk for diabetes. [31] OHCPs should also refer their patients to physicians who respond poorly to initial periodontal therapy or have advanced periodontitis without obvious signs of poor oral hygiene for diabetes screening.…”

Section: Discussionmentioning

confidence: 99%

Awareness among health care professionals regarding interrelationship between diabetes mellitus and periodontal diseases: A step towards interprofessional collaborative practice

Bains

Chandra²,

Jamaluddin³

et al. 2020

AJOHAS

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Objectives: The objective of the study was to assess the level of awareness among health care professionals regarding interrelationships between diabetes mellitus (DM) and periodontal diseases. Material and Methods: A self-administered, structured questionnaire based on scientific literature, and practice was distributed among 100 non-oral health care professionals (NOHCP) and 100 oral-health care professionals (OHCP) for assessment of their awareness regarding DM and periodontitis interrelationship (DPI). One hundred fifty-four (154) participants who responded and returned the questionnaire were interviewed to avoid any obscurity pertinent to the questionnaire and to obtain their suggestions or recommendations. Twenty-seven participant’s questionnaires were excluded due to non-availability for interview to clarify the information given. Responses of 127 participants were finally statistically analyzed. Results: Almost 79% of OHCPs were aware of the DPI. About 9% of OHCPs did not agree with DPI and 11% of them were “unaware” about the DPI. Similarly, about 65% of NOHCPs were aware of the DPI. About 15% of OHCPs did not agree with DPI and 19% of OHCPs were “unaware” about the DPI. Conclusion: A limited awareness was observed among health care professionals participating in the present study for DPI, highlighting a gap of knowledge, attitude, and practice for DPI, which was higher among NOHCP than OHCPs.

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Diabetes and Periodontal Disease: An Update for Health Care Providers

Cited by 23 publications

References 32 publications

Diagnosis and detection of VicK gene in Streptococcus mutans isolated from the saliva of patients with diabetic type 2 with tooth decay in the Iraqi population

Diagnosis and detection of VicK gene in Streptococcus mutans isolated from the saliva of patients with diabetic type 2 with tooth decay in the Iraqi population

Severity of Alveolar Bone Loss in Control and Uncontrolled Type II Diabetics

Awareness among health care professionals regarding interrelationship between diabetes mellitus and periodontal diseases: A step towards interprofessional collaborative practice

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