Diabetes and periodontal disease: a two-way relationship

Casanova, Leticia; Hughes, Francis J.; Preshaw, Philip M.

doi:10.1038/sj.bdj.2014.907

Cited by 257 publications

(230 citation statements)

References 40 publications

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“…Previous research has identified a relationship between periodontal disease and other systemic conditions, including diabetes and cardiovascular disease. 42,43 The association between diabetes and periodontal disease reported in several of the papers reviewed herein relates to the possible bidirectional relationship between diabetes and periodontal disease. 42 Significant associations of risk factors with the presence of severe periodontal disease and extent of severe periodontal destruction; being male was significantly associated with severe periodontal destruction Smith et al 18 Smoking, dental hygiene No association of risk factors with the presence of oral disease (periodontal disease or caries) Endean et al 26 Diabetes Significant associations between diabetes and higher levels of periodontal disease and missing teeth Jamieson et al 30 Substance use, dental service utilisation, dental behaviours, gender…”

Section: Risk Factors For Oral Diseasementioning

confidence: 99%

Caries and periodontal disease in Indigenous adults in Australia: a case of limited and non-contemporary data

Silva¹,

Martin-Kerry

McKee³

et al. 2017

Aust. Health Review

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Objective. The aim of the present study was to identify all evidence about the prevalence and severity of clinically measured caries and periodontal disease in Indigenous adults in Australia published in peer-reviewed journals and to summarise trends over time. In addition, we examined whether the studies investigated associations between putative risk factors and levels of caries and periodontal disease.Methods. PubMed was searched in September 2014, with no date limitations, for published peer-reviewed articles reporting the prevalence rates and/or severity of caries and periodontal disease in Indigenous adults living in Australia. Articles were excluded if measurement was not based on clinical assessment and if oral disease was reported only in a specific or targeted sample, and not the general population.Results. The search identified 18 papers (reporting on 10 primary studies) that met the inclusion criteria. The studies published clinical data about dental caries and/or periodontal disease in Australian Indigenous adults. The studies reported on oral health for Indigenous adults living in rural (40%), urban (10%) and both urban and rural (50%) locations. Included studies showed that virtually all Indigenous adults living in rural locations had periodontal disease. The data also showed caries prevalence ranged from 46% to 93%. Although 10 studies were identified, the peer-reviewed literature was extremely limited and no published studies were identified that provided statistics for a significant proportion of Australia (Victoria, Tasmania, Queensland or the Australian Capital Territory). There were also inconsistencies in how the data were reported between studies, making comparisons difficult.Conclusions. This review highlights a lack of robust and contemporary data to inform the development of policies and programs to address the disparities in oral health in Indigenous populations living in many parts of Australia.What is known about the topic? Many studies report that Indigenous people in Australia have poorer general health compared with non-Indigenous people. What does this paper add? This paper documents the available caries and periodontal disease prevalence and experience for Indigenous adults in Australia published in peer-reviewed journals. It demonstrates significant limitations in the data, including no data in several large Australian jurisdictions, inconsistency with reporting methods and most data available being for Indigenous adults living in rural locations. Therefore, the oral health data available in the peer-reviewed literature do not reflect the situation of all Indigenous people living in Australia. What are the implications for practitioners? It is important for oral health practitioners to have access to current and relevant statistics on the oral health of Indigenous Australians. However, we have highlighted significant evidence gaps for this population group within the peer-reviewed literature and identified the limitations of the available data upon which INDIGENOUS HEAL...

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Section: Risk Factors For Oral Diseasementioning

confidence: 99%

Caries and periodontal disease in Indigenous adults in Australia: a case of limited and non-contemporary data

Silva¹,

Martin-Kerry

McKee³

et al. 2017

Aust. Health Review

View full text Add to dashboard Cite

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“…5 Evidence indicates a "two-way" relationship between T2DM and CP. 6,7,8,9 A large number of epidemiological studies have demonstrated that T2DM may increase the risk of CP by two-to three-fold. 10,11,12 Conversely, CP may be a risk factor for worsened glycemic control in diabetic individuals and may increase the risk of related complications.…”

Section: Introductionmentioning

confidence: 99%

Glycemic control and adipokines after periodontal therapy in patients with Type 2 diabetes and chronic periodontitis

Wang

Liu²,

Zhang³

et al. 2017

Braz. oral res.

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Abstract:The mechanism by which chronic periodontitis (CP) affects type 2 diabetes (T2DM) remains unclear. Therefore, the aim of this study is to evaluate the effects of periodontal therapy (PT) on the glycemic control and adipokines of patients with T2DM and CP with the purpose of elucidating the possible mechanisms by which CP influences T2DM. Forty-four patients with T2DM and CP were randomly divided into two groups according to whether they underwent PT. Periodontal status, blood glucose, and the levels of serum tumor necrosis factor α (TNF-α), interleukin-6 (IL-6), adiponectin (APN), and fibroblast growth factor-21 (FGF-21) were measured at baseline and after 3 months. The results revealed that the probing depth (PD) and attachment loss (AL) were significantly improved, the serum levels of TNF-α and IL-6 were significantly decreased, and APN and FGF-21 exhibited substantial increases in the intervention group after 3 months (p < 0.05), whereas no significant changes were observed in the control group. The glycated hemoglobin (HbA1c) levels in both groups decreased significantly after 3 months compared with baseline (p < 0.05), but the intervention group exhibited a significantly greater change (p < 0.05). In conclusion, PT may relieve periodontal inflammation, which causes a reduction of insulin-antagonizing adipokines and an increase in insulin-sensitizing adipokines, thereby eliciting an improvement in glycemic control.

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“…In 1990, Shlossman et al demonstrated an increase in the prevalence of periodontitis in patients with DM2 [19]. Control of blood glucose directly influences the increased risk of periodontal disease.…”

Section: Effects Of Dm On Periodontitismentioning

confidence: 99%

Periodontal Disease And Its Impact on Health, From Cardiovascular Diseases to Metabolic Syndrome

Deschamps¹,

González²,

Durán³

et al. 2017

IOSR JDMS

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Diabetes and periodontal disease: a two-way relationship

Cited by 257 publications

References 40 publications

Caries and periodontal disease in Indigenous adults in Australia: a case of limited and non-contemporary data

Caries and periodontal disease in Indigenous adults in Australia: a case of limited and non-contemporary data

Glycemic control and adipokines after periodontal therapy in patients with Type 2 diabetes and chronic periodontitis

Periodontal Disease And Its Impact on Health, From Cardiovascular Diseases to Metabolic Syndrome

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