Diabetes and Hypertension: A Comparative Review of Current Guidelines

Cryer, Michael; Horani, Tariq; DiPette, Donald J.

doi:10.1111/jch.12638

Cited by 111 publications

(77 citation statements)

References 23 publications

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“…In this study, we acknowledged older age, overweight, low education and income, smoking, and family status as risk factors for hypertension. Similar risk factors for hypertension were identified in other studies [ 43 , 44 ]. The participants with hypertension more often resided on streets with heavy traffic for longer than 20 years.…”

Section: Discussionsupporting

confidence: 86%

Neighborhood Social and Built Environment and Disparities in the Risk of Hypertension: A Cross-Sectional Study

Gražulevičienė

Gražulevičius

Dėdelė

2020

IJERPH

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Citizens’ participation in urban environmental quality assessment is important when identifying local problems in the sustainable development and environmental planning policy. The principal aim of this study was to analyze whether any social differences exist between the joint effect of built neighborhood quality and exposure to urban green spaces and the risk of hypertension. The study sample consisted of 580 participants residing in 11 districts in Kaunas city, Lithuania. Using geographic information systems (GIS), individual data on the socioeconomic status (SES) and health were linked to the participants’ perceptions of the environmental quality and exposure to green spaces (NDVI). We used multivariate logistic regression to estimate associations as odds ratios (OR). Those study participants with lower education and those study participants with higher education on low incomes rated their health significantly worse. Low SES persons residing in areas with low exposure to green spaces had a significantly higher risk of hypertension when sex, age, family status, smoking, and income were accounted for (OR 1.83, 95% CI 1.01–3.36). This citizen science study provided evidence that the social environment and the quality of the built environment had a complex effect on disparities in the risk of hypertension.

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Section: Discussionsupporting

confidence: 86%

Neighborhood Social and Built Environment and Disparities in the Risk of Hypertension: A Cross-Sectional Study

Gražulevičienė

Gražulevičius

Dėdelė

2020

IJERPH

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“…It is noteworthy, however, that this interaction was not found in another meta-analysis focusing on patients at high CV risk, which rather showed a trend for slightly greater reduction in major cardiovascular events (MACEs) among patients with T2D versus patients without diabetes [10]. Finally, despite the well demonstrated benefit of lowering BP in diabetes [11], BP targets in patients with T2D [12] as well in patients with high CV risk [13] remain controverted, so that targets may vary between guidelines [14].…”

Section: Introductionmentioning

confidence: 89%

Effects of reducing blood pressure on cardiovascular outcomes and mortality in patients with type 2 diabetes: Focus on SGLT2 inhibitors and EMPA-REG OUTCOME

Scheen

2016

Diabetes Research and Clinical Practice

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Please cite this article as: A.J. Scheen, Effects of reducing blood pressure on cardiovascular outcomes and mortality in patients with type 2 diabetes: focus on SGLT2 inhibitors and EMPA-REG OUTCOME, Diabetes Research and Clinical Practice (2016), doi: http://dx.doi.org/10.1016/j.diabres. 2016.09.016 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. SummaryEmpagliflozin, a sodium-glucose cotransporter type 2 (SGLT2) inhibitor, has shown a remarkable reduction in cardiovascular and all-cause mortality in patients with type 2 diabetes (T2D) and antecedents of cardiovascular disease in the EMPA-REG OUTCOME trial. This effect has been attributed to a hemodynamic rather than a metabolic effect, partly due to the osmotic/diuretic effect of empagliflozin and to the reduction in arterial blood pressure. The present review will : 1) summarize the results of specific studies having tested the blood pressure lowering effects of SGLT2 inhibitors; 2) describe the results of meta-analyses of trials having evaluated the effects on mortality and cardiovascular outcomes of lowering blood pressure in patients with T2D, with a special focus on baseline and target blood pressures; 3) compare the cardiovascular outcome results in EMPA-REG OUTCOME versus other major trials with antihypertensive agents in patients with T2D; and 4) evaluate post-hoc analyses from EMPA-REG OUTCOME, especially subgroups of patients of special interest regarding the blood pressure lowering hypothesis. Although BP reduction associated to empagliflozin therapy may partly contribute to the benefits reported in EMPA-REG OUTCOME, other mechanisms most probably play a greater role in the overall CV protection and reduction in mortality observed in this trial.

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“…1 Some of the most common comorbid medical conditions with T2DM include overweight and obesity, sleep apnea, cardiovascular disease, kidney disease, hypertension and hyperlipidemia. [2][3][4][5] T2DM is also associated with increased risks of psychiatric conditions such as depression and binge eating disorder (BED). [6][7][8] BED was first added to the Diagnostic and Statistical Manual of Mental Disorders (DSM) in 1994 as a feature of eating disorder not otherwise specified (EDNOS), and did not gain formal recognition as its own psychiatric condition until 2013 in the DSM-5.…”

Section: Introductionmentioning

confidence: 99%

<p>Binge Eating Disorder in Patients with Type 2 Diabetes: Diagnostic and Management Challenges</p>

Chevinsky¹,

Wadden²,

Chao³

2020

DMSO

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Type 2 diabetes mellitus (T2DM) is associated with an increased risk of disordered eating behaviors including binge eating disorder (BED). Comorbid BED in patients with T2DM has been associated with adverse clinical outcomes such as higher body mass index (BMI) and depressive symptoms. Identifying and addressing this disorder in patients with T2DM is a significant challenge for health-care providers. The purpose of this narrative review is to discuss current perspectives on BED in the context of T2DM with implications for screening and management of these highly comorbid conditions. BED continues to be underrecognized and underdiagnosed. However, there are established tools that providers can use to screen for BED such as the SCOFF Questionnaire and Questionnaire on Eating and Weight Patterns-5. There are several effective treatments for BED including cognitive behavioral therapy, interpersonal therapy, and lisdexamfetamine dimesylate. However, few studies have examined the effects of these treatments in patients with co-morbid T2DM and BED.

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Diabetes and Hypertension: A Comparative Review of Current Guidelines

Cited by 111 publications

References 23 publications

Neighborhood Social and Built Environment and Disparities in the Risk of Hypertension: A Cross-Sectional Study

Neighborhood Social and Built Environment and Disparities in the Risk of Hypertension: A Cross-Sectional Study

Effects of reducing blood pressure on cardiovascular outcomes and mortality in patients with type 2 diabetes: Focus on SGLT2 inhibitors and EMPA-REG OUTCOME

<p>Binge Eating Disorder in Patients with Type 2 Diabetes: Diagnostic and Management Challenges</p>

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