Diabetes and Hyperglycemia in Seneca Indians

Doeblin, Thomas D.; Evans, Kathleen; Ingall, Gillian B.; Dowling, Kathleen; Chilcote, Max E.; Elsea, William R.; Bannerman, Robin M.

doi:10.1159/000152276

Cited by 18 publications

(5 citation statements)

References 7 publications

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“…The Seneca diabetics do show evidence of diabetic vascular disease (unpublished observations) but the incidence of juvenile-onset and ketosis-prone diabetes is low. 5 Inasmuch as a similar pattern of increased insulin secretion has DIABETES, VOL. 18, NO.…”

Section: Discussionmentioning

confidence: 99%

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Diabetes in the Seneca Indians: Plasma Insulin Responses to Oral Carbohydrate

1969

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In a group of adult Seneca Indians living in Western New York, 14 per cent were discovered to have previously diagnosed diabetes, and 20 per cent of the remainder had a plasma glucose of 200 mg. per 100 ml. or greater one hour after oral carbohydrate. This report describes the glucose and insulin responses to oral carbohydrate in fifty of these subjects who were not previously known to have diabetes during initial testing.On the basis of the results of a two-hour oral glucose tolerance test, forty-six subjects were classified into "diabetic" or "normal" categories. Four persons formed an intermediate group. The diabetics differed from the normals in that (1) they were older and more obese, though even the normal population was significantly obese, and (2) the mean fasting plasma insulin level was three times greater and the insulin response to oral glucose two and one-half times greater than in normals. When diabetics were subdivided on the basis of obesity or degree of glucose intolerance, no significant differences in insulin secretion could be detected. A group of diabetic subjects with a degree of obesity comparable to that of normal subjects still demonstrated two-fold increases in both fasting and postglucose insulin levels.The elevated insulin levels of diabetics can be explained only in part by co-existent obesity and suggest the presence of insulin resistance associated with diabetes in these Indians. DIABETES 18:38-43, January, 1969.

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Section: Discussionmentioning

confidence: 99%

“…4 A recent survey of Seneca Indians has also shown a high prevalence of diabetes. 5 6 Two thirds of the Senecas do not specifically admit to the knowledge of white ancestors, however, and identity as Indians is clearly maintained.…”

Section: Discussionmentioning

confidence: 99%

Diabetes in the Seneca Indians: Plasma Insulin Responses to Oral Carbohydrate

1969

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“…Neel did not suggest that the thrifty genotype was uniquely found in particular racial or ethnic groups. However, as Paradies et al (2007: 209-10) discuss in their historical review of the thrifty genotype hypothesis, other researchers did suggest that Native Americans in particular were susceptible to diabetes because they had a thrifty genotype (Doeblin et al, 1969;Johnson and McNutt, 1964). In fact, Neel emphasized that dietary changes associated with Western lifestyles are the major factor behind the diabetes epidemic in Native American communities (Neel, 1999).…”

Section: Native Americans Diabetes Risk and The Thrifty Genotype Hypothesismentioning

confidence: 99%

Genetic histories: Native Americans’ accounts of being at risk for diabetes

Sahota

2012

Soc Stud Sci

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In an age of genetic medicine, ethnic groups are increasingly being labeled at risk for chronic diseases. Biomedical and genetics research studies have had a significant impact on Native Americans’ perceptions of diabetes risk. Ethnographic interviews with 53 Native Americans were conducted in a tribal community that has participated extensively in studies of diabetes. Tribal members had varying reactions to research labeling them at risk genetically for diabetes, from fatalism to motivation for changing diet/exercise habits. Interviewees spontaneously discussed the ‘thrifty genotype’ hypothesis in diverse ways. Some felt Native Americans had ‘weak genes’ that made them ‘poorly adapted’ to modern society’s diet, while others stated that Native Americans had ‘survival genes’ that historically helped them thrive in harsh environments. Interviewees used genetics as a metaphor for expressing vulnerability in the face of a challenging history that resulted in rapid changes to Native American lifestyles. Interestingly, some tribal members saw biomedical research as a tool to help them ‘adapt’ to the modern world. Collaborative research may provide tribes with unique opportunities to actively address the diabetes epidemic. Researchers’ and healthcare providers’ descriptions of diabetes risk have important implications for how community members perceive their ability to prevent or manage the disease.

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“…Uma grande incidência de diabetes mellitus foi descrita para as populações indígenas norte-americanas, Pima (2,13,14,22,28,34), Cocopah (21,30,34), Cherokee (21,30,34), Seneca (5,8,34), Umatillo do Oregon (12,25), Alabama Coushatta (12,25), Choctaw (7,21,34), Seminole (15,21,34,35), Kiowa (29,34), Comanche (29,34), Yuma (13,28,34), Hualapi (28,34), Washoe (1,34), Paiute (1,21,34), Winnebago (33,34), Maricopa (3,34), Havasupi (28,34), Chemehuevi (3,21,34)…”

Section: O Diabetes Mellitus Entre Os 1ndi0s Dos Estados U Idos E Os ...mentioning

confidence: 99%

“…A dieta alimentar dos índios Seneca é semelhante à dos norte-americanos não índios. Observou-se que muitos Seneca eram obesos; 32 % dos já previamente diagnosticados como diabéticos apresentavam peso 30% acima da média dos Estados lJnidos, de acordo com altura, e 30% dos não diabéticos eram obesos (5) . Os diabéticos com obesidade mostraram aumento da glicemia de jejum e pós-ingestão duas vezes maior que o grupo de in , diví , duos normais ( 8) .…”

Section: O Diabetes Mellitus Entre Os 1ndi0s Dos Estados U Idos E Os ...unclassified

O diabetes Mellitus entre os índios dos Estados Unidos e os do Brasil

Filho¹

1978

Rev. antropol.

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Diabetes and Hyperglycemia in Seneca Indians

Cited by 18 publications

References 7 publications

Diabetes in the Seneca Indians: Plasma Insulin Responses to Oral Carbohydrate

Diabetes in the Seneca Indians: Plasma Insulin Responses to Oral Carbohydrate

Genetic histories: Native Americans’ accounts of being at risk for diabetes

O diabetes Mellitus entre os índios dos Estados Unidos e os do Brasil

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