Diabetes and Autonomic Neuropathy

Macleod, Andrew; Cook, Angela C

doi:10.1002/9781118405550.ch6

Cited by 2 publications

(3 citation statements)

References 56 publications

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“…Additionally, some underlying mechanisms related to type 2 DM with UI may be associated with urge UI and explain how DM gives rise to an increase in the development of UI. Such features may suggest that the association between type 2 DM and microvascular damage may affect the pelvic floor and lead to dysfunction of bladder or sphincter muscles (Torimoto et al , ; Macleod, ). In light of such findings in the literature, we believe that all poor outcomes of hyperglycaemia arise from poor progression of glycaemic control and lead to increased LUTS.…”

Section: Resultsmentioning

confidence: 99%

“…The effect of HbA1c on total BFLUTS‐SF scores is believed to stem from poor progression of glycaemic control, and polyuria is the reason for LUTS as a result of the osmolarity diuresis effect, metabolic perturbation, microvascular damage and diabetic neuropathy. It is also suggested that all of these factors contribute to dysfunction of the detrusor smooth muscle cells, urothelium and neuronal components, as well as symptomatic urinary tract infections or asymptomatic bacteriuria (Kirschner‐Hermanns et al , ; Macleod, ). Additionally, some underlying mechanisms related to type 2 DM with UI may be associated with urge UI and explain how DM gives rise to an increase in the development of UI.…”

Section: Resultsmentioning

confidence: 99%

“…Although the association between hyperglycaemia and deteriorating autonomic nerve function is well‐established, the underlying mechanisms by which hyperglycaemia causes damage still remain unclear. Hyperglycaemia is a causative factor and improved blood glucose control is believed to reduce the prevalence of autonomic neuropathy, as with other chronic complications of diabetes (Macleod, ). In various studies, it is emphasized that neuropathy influences bladder functions, giving rise to impaired sensation of bladder fullness, increased bladder capacity, reduced bladder contractility and elevated post‐void residual urine volume (Torimoto et al , ).…”

Section: Introductionmentioning

confidence: 99%

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Lower urinary tract symptoms in diabetic women with and without urinary incontinence

Yılmaz

Bal

Çelik

et al. 2014

Int J of Uro Nursing

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Determination of lower urinary tract symptoms (LUTS) in diabetic women with and without urinary incontinence (UI) and its related factors is significant to define essential measures associated with prevention. The aim of this study is to compare the features of diabetes mellitus (DM) in diabetic women with and without UI, and to investigate LUTS and its related factors. Applying to the Diabetes Department of Istanbul Medical Faculty, Istanbul University (IMFIU) between May and December 2011, 77 diabetic women with the complaint of UI and 88 diabetic continent women were enrolled into the descriptive study. Data were collected via a questionnaire defining socio‐demographic and clinical features, and The Bristol Female Lower Urinary Tract Symptoms (BFLUTS‐SF) after obtaining an approval from the ethical board of the institution. It was found that diabetic continent women and those with UI showed no statistically significant difference regarding age, BMI and duration of DM (p > 0·05). Among women with UI, levels of fasting blood glucose and HbA1c were significantly higher (p < 0·05). The total BFLUTS‐SF and subscale scores of women with UI were significantly higher than continent women (p < 0·05). A significant correlation was determined between total BFLUTS‐SF score, and fasting blood glucose (r = 0·185), BMI (r = 0·192), HbA1c (r = 0·245), complaint of vaginal itching (r = 0·629) and exposure to frequent vaginal infections (r = 0·701; p < 0·05). It was found that increased HbA1c was effective on total BFLUTS‐SF. Consequently, diabetic women with UI show high rates of fasting blood glucose and HbA1c, compared to diabetic women without UI. Therefore, diabetic women should meticulously be followed and evaluated in terms of LUTS by health care professionals.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Lower urinary tract symptoms in diabetic women with and without urinary incontinence

Yılmaz

Bal

Çelik

et al. 2014

Int J of Uro Nursing

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Cognitive impairment in patients with diabetes

Wilson

2012

Nursing Standard

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Type land type 2 diabetes are associated with major complications that shorten life expectancy. Fluctuations in the amount of glucose reaching the brain cause a wide range of alterations to cerebral function, from mild impairment through to dementia-like states and even death. The responsibility is on the patient with diabetes to control his or her blood glucose levels to reduce any mental decline. However, nursing staff should be aware that patients with diabetes experiencing a loss of mental function may have difficulty in understanding information and instructions. This article examines the current literature on loss of mental function as a chronic complication of diabetes.

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Diabetes and Autonomic Neuropathy

Cited by 2 publications

References 56 publications

Lower urinary tract symptoms in diabetic women with and without urinary incontinence

Lower urinary tract symptoms in diabetic women with and without urinary incontinence

Cognitive impairment in patients with diabetes

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