Abstract:BackgroundAplastic anaemia comes from a bone marrow failure which affects all blood lineages. Treatment is based on immunosuppression or allogeneic transplant, but some patients are refractory to these options. Eltrombopag, a thrombopoietin receptor agonist administered orally, promotes megakaryopoiesis and platelet release.PurposeTo assess eltrombopag effectiveness as off-label treatment for immunosuppression-refractory aplastic anaemia.Material and methodsA 10-month (1/12/2013–30/09/2014) retrospective study… Show more
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