Abstract:BackgroundAn adverse drug event (ADE) is a potentially harmful and unintended outcome of medicines use. In the UK, ADE trigger tools have been advocated for detecting ADEs associated with high risk drugs, including opioids. Naloxone is used to reverse opioid toxicity so is a useful indicator of potential opioid related ADEs.PurposeWe aimed to measure the sensitivity of naloxone as a trigger to detect opioid related ADEs in adult inpatients in an acute hospital. The objectives were to: assess the positive predi… Show more
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