Abstract:ObjectiveNo efficacious treatments exist to improve or prolong bulbar functions of speech and swallowing in persons with amyotrophic lateral sclerosis (pALS). This study evaluated the short‐term impact of dextromethorphan/quinidine (DMQ) treatment on speech and swallowing function in pALS.MethodsThis was a cohort trial conducted between August 2019 to August 2021 in pALS with a confirmed diagnosis of probable‐definite ALS (El‐Escorial Criteria‐revisited) and bulbar impairment (ALS Functional Rating Scale score… Show more
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