2024
DOI: 10.1016/j.carbpol.2023.121700
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Dextran and levan exopolysaccharides from tempeh-associated lactic acid bacteria with bioactivity against enterotoxigenic Escherichia coli (ETEC)

Theodorus Eko Pramudito,
Krishna Desai,
Camiel Voigt
et al.
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Cited by 2 publications
(1 citation statement)
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“…Most importantly, SoSa I reduced the bacterial load of E. coli in the intestinal tract, which is a direct indicator of ETEC infection severity. 1 ETEC infection is known to damage the intestinal mucosa, 45 increase intestinal epithelial cell permeability, 17,46 facilitate bacterial toxin translocation 47 and entry into the circulatory system, 48 and increase serum endotoxin, 49 and d -lactic acid levels, 50 ultimately causing intestinal dysfunction. Our findings indicate that SoSa I effectively lowers endotoxin and d -lactic acid levels, enhances the antioxidant capacity, decreases the expression of intestinal inflammatory factors, and improves intestinal function.…”
Section: Discussionmentioning
confidence: 99%
“…Most importantly, SoSa I reduced the bacterial load of E. coli in the intestinal tract, which is a direct indicator of ETEC infection severity. 1 ETEC infection is known to damage the intestinal mucosa, 45 increase intestinal epithelial cell permeability, 17,46 facilitate bacterial toxin translocation 47 and entry into the circulatory system, 48 and increase serum endotoxin, 49 and d -lactic acid levels, 50 ultimately causing intestinal dysfunction. Our findings indicate that SoSa I effectively lowers endotoxin and d -lactic acid levels, enhances the antioxidant capacity, decreases the expression of intestinal inflammatory factors, and improves intestinal function.…”
Section: Discussionmentioning
confidence: 99%