Dexmedetomidine vs. Fentanyl as Adjuvant to Local Anaesthetic Mixture in Peribulbar Block for Retinal Surgery: A Randomized Prospective Study

Khalil, Naglaa; Marouf, Hesham M

doi:10.4172/2155-6148.1000755

Cited by 1 publication

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References 20 publications

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“…Hence, the absolute amount of long-acting LA administered was lesser than in our study. Khalil et al ,[ 18 ] found lower post-operative pain scores in the first 6 hours and lesser analgesic consumption when dexmedetomidine was added to PBB. The scleral buckling procedures were associated with earlier demand for pain relief.…”

Section: Discussionmentioning

confidence: 99%

Effect of adding dexmedetomidine to 0.75% ropivacaine in peribulbar block for vitreoretinal surgery

Subramanian

Bapat

Braganza

et al. 2022

J Anaesthesiol Clin Pharmacol

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Background and Aims: Peribulbar anesthesia is suitable for vitreoretinal (VR) surgery. Dexmedetomidine has been used in peribulbar block (PBB) to improve akinesia and analgesia. We aimed to study the efficacy of adding dexmedetomidine to 0.75% Ropivacaine in PBB for VR surgery. The primary outcome was the requirement of block supplementation and secondary outcome was post-operative analgesic requirement. Material and Methods: 100 adult patients undergoing VR surgery were included in this prospective randomized double-blinded controlled study. The composition of the drug used for PBB in the 3 groups was Group R (8 ml of 0.75% Ropivacaine +0.5 ml normal saline (NS)), Group D25 (8 ml of 0.75% Ropivacaine +25μg Dexmedetomidine) and Group D50 (8 ml of 0.75% Ropivacaine +50 μg Dexmedetomidine). Results: The groups were comparable in terms of patient demographics. The requirement for block supplementation was 16.7% in Group R (5/30), 12.5% in Group D25 (4/32) and 8.8% in group D50 (3/34) ( P = 0.64). The mean time to first request for post-operative analgesia was432 ± 362 min in Group R, 572 ± 339 min in Group D25 and 614 ± 394 min for Group D50 ( P = 0.26). There was significant difference in the heart rate ( P = 0.047), mean arterial pressure (P = 0.012) at 30 min and sedation (RASS) score at 15, 30, 60 ( P < 0.001) and 120 ( P = 0.019) min between the D50 and group R. Patients undergoing buckling procedures had significantly shorter time to request for analgesia ( P = 0.003). Conclusion: Addition of dexmedetomidine does not offer advantage over 0.75% Ropivacaine in PBB for vitrectomy. Its benefit in more painful procedures like scleral buckle needs further validation.

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Section: Discussionmentioning

confidence: 99%

Effect of adding dexmedetomidine to 0.75% ropivacaine in peribulbar block for vitreoretinal surgery

Subramanian

Bapat

Braganza

et al. 2022

J Anaesthesiol Clin Pharmacol

View full text Add to dashboard Cite

show abstract

Dexmedetomidine vs. Fentanyl as Adjuvant to Local Anaesthetic Mixture in Peribulbar Block for Retinal Surgery: A Randomized Prospective Study

Abstract: Background and aims: we aimed to compare the effects of adding dexmedetomidine vs. fentanyl as adjuvants to local anesthetic mixture in peribulbar block for retinal surgery.

Cited by 1 publication

References 20 publications

Effect of adding dexmedetomidine to 0.75% ropivacaine in peribulbar block for vitreoretinal surgery

Effect of adding dexmedetomidine to 0.75% ropivacaine in peribulbar block for vitreoretinal surgery

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