Dexamethasone Intravitreal Implant in Patients with Macular Edema Due to Central Retinal Vein Occlusion: Six Months Results

Abstract

30antral retinal ven tıkanıklığı (SRVT), retina ven dal tıkanıklığından (RVDT)'dan daha az görülmesine rağmen, görme keskinliğinde azalma yapan ve sık görülen bir retina damarsal hastalığıdır. A An na ah ht ta ar r K Ke el li im me el le er r: : İntravitreal enjeksiyon; makula ödemi; retinal ven tıkanıklığı A AB BS ST TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To determine six-month results after a single application of dexamethasone intravitreal implant used in macular edema following central retinal vein occlusion (CRVO). M Ma a--t te er ri ia al l a an nd d M Me et th ho od ds s: : The findings of 22 eyes of 22 patients diagnosed (ME) macusluar edema following control retinal vein occlusion CRVO were evaluated retrospectively. Patients were examined in 1, 7, 30, 90 and 180 days after injection. The best visual acuity of patients was measured by Snellen chart at each visit, and the results were converted to ETDRS letters scoring. Biomicroscopy, tonometry, fundoscopy and optic coherence tomography (OCT) were made in every visit. R Re es su ul lt ts s: : Visual acuity increase was 1.1±1.5, 2.9±1.8, 8.5±1.9, 9.8±4.7, 8.0±1.8, 4.0±1.3 letters in 1 st , 7 th , 30 th , 60 th , 90 th and 180 th day respectively. The maximum response of the patients visual acuity was observed in the second month and visual acuity increase began to decline from the third month. The reduction in macular thickness in patients was 14±7.8, 71±12.8, 132±11.4, 205±5.4, 140±6.6, 120±7.6 μm in day 1, 7, 30, 60, 90 and 180 respectively. Macular thickness showed an increase trend after third months. C Co on nc cl lu us si io on n: : Clinically significant improvement in visual acuity and macular thickness reduction is provided with single application of dexamethasono intravitreal implant IVD. This positive effect reached the maximum level in third months and started to decrease by sixth months.