Dexamethasone as Treatment in Cerebrovascular Disease. 2. A Controlled Study in Acute Cerebral Infarction

Bauer, Robert O.; Tellez, Henry

doi:10.1161/01.str.4.4.547

Cited by 113 publications

(29 citation statements)

References 9 publications

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“…No evidence indicates that hyperventilation, corticosteroids in conventional or large doses, furo-semide, mannitol, or glycerol or other measures that reduce intracranial pressure improve outcome in patients with ischemic brain swelling. [681][682][683][684][685][686][687][688][689][690] Mannitol is typically used at 0.25 to 0.5 g/kg IV administered over 20 minutes, lowers intracranial pressure, and can be given every 6 hours. 691 The usual maximal dose is 2 g/kg.…”

Section: A Ischemic Brain Swellingmentioning

confidence: 99%

Guidelines for the Early Management of Adults With Ischemic Stroke

Adams

Zoppo²,

Alberts

et al. 2007

Stroke

2,118

483

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Section: A Ischemic Brain Swellingmentioning

confidence: 99%

Guidelines for the Early Management of Adults With Ischemic Stroke

Adams

Zoppo²,

Alberts

et al. 2007

Stroke

2,118

483

View full text Add to dashboard Cite

show abstract

“…[681][682][683][684][685][686][687][688][689][690] Mannitol is typically used at 0.25 to 0.5 g/kg IV administered over 20 minutes, lowers intracranial pressure, and can be given every 6 hours. 691 The usual maximal dose is 2 g/kg.…”

Section: Adams Et Al Early Management Of Adults With Ischemic Stroke mentioning

confidence: 99%

Guidelines for the Early Management of Adults With Ischemic Stroke

Adams¹,

Zoppo²,

Alberts³

et al. 2007

Circulation

1,059

745

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Purpose-Our goal is to provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke. The intended audience is physicians and other emergency healthcare providers who treat patients within the first 48 hours after stroke. In addition, information for healthcare policy makers is included. Key Words: AHA Scientific Statements Ⅲ emergency medical services Ⅲ stroke Ⅲ acute cerebral infarction Ⅲ tissue plasminogen activator †Deceased. The American Heart Association makes every effort to avoid any actual or potential conflicts of interest that may arise as a result of an outside relationship or a personal, professional, or business interest of a member of the writing panel. Specifically, all members of the writing group are required to complete and submit a Disclosure Questionnaire showing all such relationships that might be perceived as real or potential conflicts of interest. Methods-Members

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“…Although several trials in patients with presumed ischemic stroke have failed to show a reduction in mortality (39)(40)(41)(42), at least one study has demonstrated a significant improvement in functional outcome (43). In experimental stroke, physiological levels of corticosteroids increase the severity of ischemic injury after global ischemia (44).…”

Section: Discussionmentioning

confidence: 99%