Devices and pressure sources for administration of nasal continuous positive airway pressure (NCPAP) in preterm neonates

Paoli, Antonio G De; Davis, Peter G; Faber, B; Morley, Colin J

doi:10.1002/14651858.cd002977.pub2

Cited by 182 publications

(105 citation statements)

References 57 publications

(1 reference statement)

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“…To our knowledge, this is the first and largest study to investigate the effects of different NCPAP interfaces on BPD where the RDS patients were treated with less invasive surfactant administration. In a Cochrane meta-analysis [12], the effect of the technique of pressure generation and the type of nasal interface for NCPAP delivery to effectively reduce the need for additional respiratory support was studied; only 1 trial identified preterm infants primarily treated with NCPAP soon after birth. Mazzella et al [25] found a significantly lower oxygen requirement and respiratory rate in infants randomized to short NP than to CPAP delivered via nasopharyngeal prong.…”

Section: Discussionmentioning

confidence: 99%

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Binasal Prong versus Nasal Mask for Applying CPAP to Preterm Infants: A Randomized Controlled Trial

Kutman

Oğuz

et al. 2016

Neonatology

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Background: Nasal continuous positive airway pressure (NCPAP) is being widely used for the treatment of respiratory distress syndrome (RDS) in preterm infants. However, there are only a few studies which compare different interfaces of NCPAP delivery and their effects on respiratory outcomes. Objective: We aimed to determine whether NCPAP applied with binasal prongs compared to that with a nasal mask (NM) reduces the rate of moderate/severe bronchopulmonary dysplasia (BPD) in preterm infants. Methods: Infants between 26 and 32 weeks' gestation who suffered from RDS and were treated with NCPAP were assessed. Parallel randomization was performed to eligible infants to receive NCPAP either via binasal prongs or NM. Infants were intubated if they fulfilled the predefined failure criteria. Data were collected by using the intention-to-treat principle. Results: One hundred and sixty infants were screened and 149 were randomized. Seventy-five infants in the binasal prong (NP) group and 74 in the NM group were analyzed. Mean gestational ages were 29.3 ± 1.6 vs. 29.1 ± 2.0 weeks (p = 0.55), and birth weights were 1,225 ± 257 vs. 1,282 ± 312 g (p = 0.22) in the NP and NM groups, respectively. The frequency of NCPAP failure within 24 h of life was higher in the NP than the NM group (8 vs. 0%; p = 0.09). The median duration of NCPAP was significantly higher in the NP group [median 4 (1-5) vs. 2 (1-3) h, p < 0.01]. The rate of moderate and severe BPD was significantly lower in the NM (n = 2, 2.7%) when compared with the NP group (n = 11, 14.6%; p < 0.01). The BPD/death rates were not different between the 2 groups (NM group: n = 18 or 24.3%; NP group: n = 19 or 25.3%; p = 0.51). Conclusions: The NM was successfully used for delivering NCPAP in preterm infants, and no NCPAP failure was observed within the first 24 h. These data show that applying NCPAP by NM yielded a shorter duration of NCPAP and statistically reduced the rates of moderate and severe BPD.

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Section: Discussionmentioning

confidence: 99%

“…The most commonly used to deliver NCPAP are prongs (NP) and masks (NM). Short binasal prongs seem to be more effective than a single NP or nasopharyngeal prongs because of the reduced resistance in the nares [11,12]. Masks that fit over the nose were developed many years ago and are commonly used today [13,14,15].…”

Section: Introductionmentioning

confidence: 99%

Binasal Prong versus Nasal Mask for Applying CPAP to Preterm Infants: A Randomized Controlled Trial

Kutman

Oğuz

et al. 2016

Neonatology

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“…In comparing the non-invasive ventilation with NIPPV to the nasal CPAP, fewer respiratory failures and the need for intubation in the NIPPV group were found [46]. Meta-analysis of the use of different devices and interfaces for CPAP has elucidated differences in outcome depending on the use of nasal adapters or interfaces, requiring further research [47]. Similarly, there is an open question whether breathing with the help of bi-level CPAP is better than breathing with CPAP alone and does it pose an advantage of better exhaling CO 2 , better oxygenation or other physiological indicators [48].…”

Section: Non-invasive Respiratory Supportmentioning

confidence: 99%

Respiratory Care of the Neonate

Grosek¹,

Fister²

2018

Selected Topics in Neonatal Care

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The respiratory distress is a very common condition both in term and in preterm neonates and the most frequent reason for admission to the neonatal intensive care unit (NICU). The aetiology greatly depends on the maturation of neonate's organs and perinatal events. The clinical picture is sometimes scarce and very nonspecific for the etiologic determination. Treatment of neonatal RD begins first with the application of a mixture of oxygen and air, then with different modes of non-invasive respiratory support methods. Non-invasive respiratory support can be sustained with nasal continuous positive airway pressure, bi-level positive airway pressure and high-flow nasal cannula ventilation. Non-invasive ventilation with high-frequency oscillations through nasal cannula or masks is also possible with some respiratory devices. Non-invasive ventilation is usually combined with the application of natural surfactant and other therapeutic means, like methylxanthine therapy, prevention and closure of patent ductus arteriosus, and control of infection. In the case of non-invasive ventilation failure, different kinds of invasive ventilation methods are available and being practiced in NICUs. The invasive respiratory support can be maintained by controlled or intermittent mandatory ventilation combined with different supportive synchronous positive inspiratory ventilation, offered by modern respirators.

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“…Se ha utilizado para tratar la apnea frecuentes o graves en los niños prematuros, los informes de casos de perforaciones gastrointestinales ha limitado su uso generalizado, parece reducir la frecuencia de apneas de manera más eficaz que el CPAP, se necesita más datos acerca de la seguridad y eficacia antes de recomendar la VNPPI como 3; N° 3; Diciembre 2016 (38) tratamiento estándar en las apneas . La Academia American de Pediatría (AAP) y la Asociación American del Corazón (AHA) recomienda lo siguiente con relación al uso de O en 2 (39) la reanimación .…”

Section: Ventilación Con Presión Positiva Intermitente Nasal (Vnppi)unclassified

"Oxygen therapy in neonates". An unresolved problem

Villamayor

2016

Pediatr. (Asunción)

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2 es un gas, sino es un fármaco, con sus indicaciones, dosis, efectos adversos y necesidades de (1) monitorización .Con relación al descubrimiento del O y su uso en la 2 medicina, se remontan a los avances en la física y la ABSTRACT Key words:The management of O2, its monitoring and the target levels for neonates, mainly premature, are discussed. It is essential that both medical and nursing staff should be well trained in order to safely and effectively use O2 in neonates in clinical practice.Oxygen therapy, administration, Newborn.

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Devices and pressure sources for administration of nasal continuous positive airway pressure (NCPAP) in preterm neonates

Abstract: Devices and pressure sources for administration of nasal continuous positive airway pressure (NCPAP) in preterm neonates.

Cited by 182 publications

References 57 publications

Binasal Prong versus Nasal Mask for Applying CPAP to Preterm Infants: A Randomized Controlled Trial

Binasal Prong versus Nasal Mask for Applying CPAP to Preterm Infants: A Randomized Controlled Trial

Respiratory Care of the Neonate

"Oxygen therapy in neonates". An unresolved problem

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