Device Selection and Outcomes of Aerosol Therapy: Evidence-Based Guidelines

Dolovich, Myrna; Ahrens, Richard C.; Hess, Dean; Anderson, Paula; Dhand, Rajiv; Rau, Joseph L.; Smaldone, Gerald C.; Guyatt, Gordon

doi:10.1378/chest.127.1.335

Cited by 676 publications

(461 citation statements)

References 106 publications

(87 reference statements)

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“…The American College of Chest Physicians and American College of Asthma, Allergy and Immunology have provided more useful advice on prescribing inhalers, recommending that a number of factors are considered when prescribing inhaler devices [55]. These factors included drug availability, patient ability to use, cost, convenience of device, device durability and patient or prescriber device preference [55].…”

Section: Choice Of Inhaler To Prescribementioning

confidence: 99%

Inhaler technique and training in people with chronic obstructive pulmonary disease and asthma

Capstick

Clifton²

2012

Expert Review of Respiratory Medicine

117

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Section: Choice Of Inhaler To Prescribementioning

confidence: 99%

Inhaler technique and training in people with chronic obstructive pulmonary disease and asthma

Capstick

Clifton²

2012

Expert Review of Respiratory Medicine

117

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“…Meta-analyses and systematic reviews [2,3,30] indicate that all inhalers can be effective and can achieve a similar therapeutic effect when patients use the inhalation technique recommended by the manufacturer, although different doses may be required. These observations are often documented in randomised controlled trials, where patients receive more inhaler-technique training and counselling on the importance of adherence than do patients in routine clinical practice.…”

Section: Resultsmentioning

confidence: 99%

“…We believe that differences in efficacy among devices become trivial in case of correct inhalation technique, as supported by evidence-based guidelines from the American College of Chest Physicians/American College of Asthma, Allergy, and Immunology [2]. The key issue is patient training and verification of the inhalation technique.…”

Section: Introductionmentioning

confidence: 93%

Which factors affect the choice of the inhaler in chronic obstructive respiratory diseases?

Scichilone

Benfante

Bocchino

et al. 2015

Pulmonary Pharmacology & Therapeutics

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a b s t r a c tInhalation is the preferred route of drug administration in chronic respiratory diseases because it optimises delivery of the active compounds to the targeted site and minimises side effects from systemic distribution. The choice of a device should be made after careful evaluation of the patient's clinical condition (degree of airway obstruction, comorbidities), as well as their ability to coordinate the inhalation manoeuvre and to generate sufficient inspiratory flow. These patient factors must be aligned with the specific advantages and limitations of each inhaler when making this important choice. Finally, adherence to treatment is not the responsibility of the patient alone, but should be shared also by clinicians. Clinicians have access to a wide selection of pressurised metered dose inhalers (pMDIs) and dry powder inhalers (DPIs) that can be used effectively when matched to the needs of individual patients; this should be perceived as an opportunity rather than a limitation.

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“…Inhaled route is the best route of corticosterioid (CS) therapy as it provides targeted drug delivery, acts faster, small dose is required and is easy to take [10,11]. Oral steroids have more side effects and have no superiority Anti IgE (omalizumab) is a treatment option limited to patients with elevated serum levels of IgE.…”

Section: Treatmentmentioning

confidence: 99%

Best Treatment Guidelines For Bronchial Asthma

Rai

Patil

Vardhan

et al. 2007

Medical Journal Armed Forces India

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Asthma is a common disease worldwide with significant ethnic and regional variations. An increasing morbidity and mortality, as well as health care burden from asthma have been recognized lately. Several evidence based guidelines have been developed with an aim to standardize and improve the quality of management. These guidelines seek to translate the advances in the understanding of pathogenesis of asthma and in the development of new agents and strategies into practical application at all levels of healthcare. These advocate an assessment of the patients to classify the severity of diseases followed by a step-wise approach to treatment. With the current management we hope to achieve minimum or nil day time and night time symptoms, prevent acute exacerbations and attain normal or near normal lung function, thus improving the overall quality of life. MJAFI 2007; 63 : 264-268

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Device Selection and Outcomes of Aerosol Therapy: Evidence-Based Guidelines

Cited by 676 publications

References 106 publications

Inhaler technique and training in people with chronic obstructive pulmonary disease and asthma

Inhaler technique and training in people with chronic obstructive pulmonary disease and asthma

Which factors affect the choice of the inhaler in chronic obstructive respiratory diseases?

Best Treatment Guidelines For Bronchial Asthma

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