Current Opinion in Hematology volume 18, issue 6, P452-460 2011 DOI: 10.1097/moh.0b013e32834babdd View full text
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Stefan Muschter, Tom Berthold, Andreas Greinacher

Abstract: Characterization of the HNA-3 system allows identification of blood donors at risk to develop HNA-3-antibodies. FcγRIIIb (HNA-1) and CD177 (HNA-2) seem to be important in bacterial host defense. Activation of neutrophils by HNA-1 and HNA-2-antibodies potentially occurs via mPR3 and CD11b/CD18 (HNA-4a).