Developments in mycotoxin analysis: an update for 2012-2013

Abstract

This review summarises developments in the determination of mycotoxins over a period between mid-2015 and mid-2016. Analytical methods to determine aflatoxins, Alternaria toxins, ergot alkaloids, fumonisins, ochratoxins, patulin, trichothecenes and zearalenone are covered in individual sections. Advances in proper sampling strategies are discussed in a dedicated section, as are methods used to analyse botanicals and spices and newly developed liquid chromatography mass spectrometry based multi-mycotoxin methods. This critical review aims to briefly discuss the most important recent developments and trends in mycotoxin determination as well as to address limitations of presented methodologies.

Identification in residue analysis based on liquid chromatography with tandem mass spectrometry: Experimental evidence to update performance criteria

“…Only when one or both product ions are in the low S/N range (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15), higher deviations are more frequently observed. Based on the 95th percentile of the RSDs obtained for the reference ion ratios, deviations up to AE45% (relative) can be expected.…”

“…Operation in multiple-reaction monitoring (MRM) mode permits the measurement of multiple analytes (typically more than 150) in a single analytical run and thus it is not surprising that LC-MS/MS has become the method of choice for routine pesticide multi-residue analysis [1,2]. This trend is also observed in the field of veterinary drugs [3][4][5], mycotoxins [6][7][8], and in food safety and quality analysis in general [9,10]. Similar developments have taken place in other analytical domains including environmental analysis [11], forensic and clinical toxicology [12,13], and in human sports doping [14,15].…”

Advanced LC–MS-based methods to study the co-occurrence and metabolization of multiple mycotoxins in cereals and cereal-based food

“…Moreover, new developments and updates in this field are covered on a yearly basis in World Mycotoxin Journal [25][26][27][28].…”

Monitoring survey of patulin in a variety of fruit-based products using a sensitive UHPLC–MS/MS analytical procedure

“…While instrumental and bio-analytical methods for detection and quantification of other regulated mycotoxins have improved significantly over the last ten years (Berthiller et al, 2014), the availability of analytical procedures for detection of patulin are still rather limited. Problematic issues in patulin analysis include purification of extracts and sensitivity of detection instrumentation (Moake et al, 2005).…”