Developments in inherent safety: A review of the progress during 2001–2011 and opportunities ahead

Srinivasan, Rajagopalan; Natarajan, Sathish

doi:10.1016/j.psep.2012.06.001

Cited by 64 publications

(22 citation statements)

References 132 publications

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“…The origin of the inherent hazards tends to be in material, process, and unit operations; however, the PRI method has focused on the process aspects only relevant to the explosion scenario . Therefore, the new index namely EPRI, is proposed which accommodates all the identified aspects and be written as:

EPRI = f (chemical, process, equipment)

The chemical aspect can be defined via the heating energy and combustibility potential of the chemicals in the process.…”

Section: Methodsmentioning

confidence: 99%

Equipment‐based route index of inherent safety

Athar

Shariff

Buang

et al. 2019

Process Safety Progress

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Process safety concept is used to deal with accident scenarios occurring as a result of loss containment. There are four tactics of process safety, and due to superior characteristics, the inherent theme is given priority at the preliminary design stage. In open literature, various methods have been proposed to identify the inherent safety level, and among these indexing methods are typically used. The reported indices have a shortcoming that these have not considered equipment characteristics for inherent safety assessment. Therefore, a new indexing method is proposed in this article to improve the quantification of inherent safety level. This index incorporates process, chemical, and equipment aspects to define the safety level of various process routes via the relative ranking. The proposed index has been tested on process routes to produce methyl methacrylate, which confirms the applicability of this index. The index would enable the practitioners to thoroughly analyze and compare the process routes to identify the inherently safer route.

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EPRI = f (chemical, process, equipment)

The chemical aspect can be defined via the heating energy and combustibility potential of the chemicals in the process.…”

Section: Methodsmentioning

confidence: 99%

Equipment‐based route index of inherent safety

Athar

Shariff

Buang

et al. 2019

Process Safety Progress

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show abstract

“…Several inherent safety and EHS hazard assessments have been proposed and compared for chemical process design . Actually, one of them, the inherent safety index (ISI), has already been used in combination with PFD .…”

Section: Methodsmentioning

confidence: 99%

Retrofit design of a pharmaceutical batch process considering “green chemistry and engineering” principles

Banimostafa¹,

Papadokonstantakis²,

Hungerbühler³

2015

AIChE Journal

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Considering the capital intensive nature of the chemical industry, redesign of existing production plants is a strategic decision. In this study, retrofitting is performed using a systematic path flow decomposition method, enriching it with hazard assessment and life cycle analysis path flow indicators and proposing a classification scheme for coupling these new path flow indicators with relevant heuristics for process alternative generation. The developed methodology is applied in a batch production plant from the pharmaceutical industry. The method highlights solvent recovery or substitution as important retrofitting actions, generates diverse process layout structures to achieve this task and evaluates them from cost, hazard and life cycle assessment point of view. Extractive distillation using glycol as an entrainer is identified as the multiobjective optimal option for separating the THF/Water azeotrope with improvement up to 40% for the various objectives compared with a base case where the waste solvent is incinerated. © 2015 American Institute of Chemical Engineers AIChE J, 61: 3423–3440, 2015

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“…Hendershot (2006) discussed the different ISD strategies with examples to provide a better understanding of how the application of ISD strategies varies from industry to industry, plant to plant and stage to stage of the process design life cycle. Review of the progress of inherent safety and its development during the period of 2001-2011 and future opportunities were thoroughly discussed by Srinivasan & Natarajan (2012).…”

Section: Introductionmentioning

confidence: 99%