Developments and applications of cyanoacrylate adhesives

Abstract

Abstract�Various developments in the synthesis of alkyl 2-cyanoacrylates, their analytical and test methods, adhesive compositions for different applications including those in the medical field, handling and storage, and health and safety hazards are reviewed.

In-Vitro Analysis for Microbial Barrier Properties of 2-Octyl Cyanoacrylate-Derived Wound Treatment Films

“…Me´thodes: Les propriétés barrières des pellicules du cyanoacrylate ont été testées par les deux méthodes suivantes : (1) pellicule pré-polymérisée et (2) pellicule polymérisée in situ. La surface extérieure de la pellicule a été inoculée de façon à ce que les microorganismes doivent pénétrer á travers la pellicule pour coloniser la plaie.…”

“…2 In order to isolate the effects of 2-octyl cyanoacrylate formulation polymerization on the agar media, two methods of film production were used. One set of films was prepolymerized in a polypropylene mold and another set was prepared by in situ polymerization on the surface of an agar growth medium.…”

“…In addition, the bond between the glass penicylinder and the cyanoacrylate adhesive may deteriorate in the presence of water. 2 Hence, during polymerization, it is possible that the 2-octyl cyanoacrylate formulation-based film shrunk and pulled away from glass penicylinder and that the aqueous inoculum further weakened the bond between the glass penicylinder and the film. Pseudomonas aeruginosa is the smallest challenge organism used in this test and is flagellated and motile.…”

Radical Polymerization of Alkyl 2-Cyanoacrylates

“…Alkyl 2-cyanoacrylates or cyanoacrylates (CAs) are a family of vinyl monomers renowned for their high reactivity, instant adhesive properties, and wide-ranging applications [1,2,3,4,5,6]. Short chain CAs, like methyl- and ethyl 2-cyanoacrylate have found great utility as the major components of industrial and household instant adhesives or “super glues”, including those manufactured at Henkel under the Loctite brand (Table 1) [4,5,6].…”

Wound Adhesive from Cyanoacrylate: Synthesis and Characterization

“…The use of cyanoacrylates has increased significantly in recent years owing to their unique combination of chemical and physical properties, namely: (1) they cure rapidly at room temperature; (2) they form strong bonds with a wide variety of different materials without the addition of a catalyst; (3) they can be easily and safely applied either manually or by automatic equipment; and (4) they are ready to use without mixing or using a primer [2]. These unique materials were discovered in 1951 in the course of applied research directed towards the characterization of stronger, tougher and more heat-resistant acrylate polymers for jet plane canopies [3].…”