Developmental stability and minor physical anomalies in schizophrenic patients

Joober, Ridha; Abid, S.; Zineb, S. Ben; Tabbane, Karim; Taktak, J.; Douki, Stamatina

doi:10.1016/s0006-3223(97)87825-0

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The use of shared decision-making in the selection of treatment is also recommended. There is modest evidence for efficacy of pharmacologic and nonpharmacologic treatments for insomnia in patients with schizophrenia [49,50], including sedating antipsychotics, melatonin [51], eszopiclone [52], and cognitive behavioral therapy for insomnia (CBT-I) [53][54][55][56]. Findings for melatonin are based on two small clinical trials comprising 23 subjects [51].…”

Section: Discussionmentioning

confidence: 99%

Meta-analysis of insomnia, suicide, and psychopathology in schizophrenia

Miller

McCall

2023

Current Opinion in Psychiatry

View full text Add to dashboard Cite

Purpose of reviewInsomnia is common in schizophrenia. Insomnia has been associated with suicidal ideation and behavior, as well as greater severity of psychopathology, in schizophrenia. This review performs a meta-analysis of associations between insomnia, suicide, and psychopathology in patients with schizophrenia.Recent findingsWe searched major electronic databases from inception until November 2022 for studies of insomnia, suicide, and psychopathology in patients with schizophrenia. Random effects meta-analysis calculating odds ratios (ORs, for suicide) and effect sizes (ESs, for psychopathology) and 95% confidence intervals (CIs) were performed. Ten studies met the inclusion criteria, comprising 3428 patients with schizophrenia. Insomnia was associated with a significant increased odds of suicidal ideation (OR = 1.84, 95% CI 1.28–2.65, P < 0.01) and suicide attempt or death (OR = 5.83, 95% CI 1.61–2.96, P < 0.01). Insomnia was also associated with total (ES = 0.16, 95% CI 0.09–0.23, P < 0.01), positive (ES = 0.14, 95% CI 0.08–0.20, P = 0.02), and general (ES = 0.17, 95% CI 0.08–0.27, P < 0.01) psychopathology. In meta-regression analyses, BMI was negatively associated with suicidal ideation. Otherwise, age, sex, and study year were all unrelated to the associations.SummaryInsomnia is associated with suicide and psychopathology in schizophrenia. Formal assessment and treatment of insomnia appears relevant to the clinical care of schizophrenia.

show abstract

Section: Discussionmentioning

confidence: 99%

Meta-analysis of insomnia, suicide, and psychopathology in schizophrenia

Miller

McCall

2023

Current Opinion in Psychiatry

View full text Add to dashboard Cite

show abstract

“…In a recent review an algorithmic approach to the management of insomnia in patients with schizophrenia is presented [37]. First of all, the etiology of insomnia must be precisely established, as well as its global functional impact on the patient.…”

Section: Theranostics Of Brain Spine and Neural Disordersmentioning

confidence: 99%

Sleep Disorders in Schizophrenia. A Review of Literature

Anmella

2017

TBSND

View full text Add to dashboard Cite

Up to 80% of patients with schizophrenia have suffered from sleep disorders (SD), which are normally under diagnosed and undertreated due to lack of consideration in the management of schizophrenia. The most common sleep disorders in schizophrenia are insomnia, restless leg syndrome (RLS), obstructive sleep apnea syndrome (OSAS), hypersomnia, parasomnia and circadian rhythm disorders. The relevance of insomnia should be emphasized, as it can be a prodromal signof schizophrenia, as well as an alarm sign of an incipient psychotic decompensation. Additionally, the clinical recovery of a psychotic process is usually correlated with sleep normalization. Multiple polysomnographic disturbances on sleep architecture have been found in patients with schizophrenia, including increased sleep latency, awakenings during sleep, sleep-wake cycle inversion, as well as poor sleep efficiency. These objective disturbances have been correlated to subjective poor sleep quality and other main clinical symptoms in schizophrenia.

show abstract

Developmental stability and minor physical anomalies in schizophrenic patients

Cited by 2 publications

References 0 publications

Meta-analysis of insomnia, suicide, and psychopathology in schizophrenia

Meta-analysis of insomnia, suicide, and psychopathology in schizophrenia

Sleep Disorders in Schizophrenia. A Review of Literature

Contact Info

Product

Resources

About